Foot ischemia related to essential thrombocytemia and atherosclerosis.
J Med Vasc
; 46(3): 123-128, 2021 May.
Article
em En
| MEDLINE
| ID: mdl-33990286
ABSTRACT
We report two cases of foot ischemia combining microvascular thrombosis related to essential thrombocytemia (ET) and a proximal ulcerating atherosclerotic plaque. This suggests that myeloproliferative neoplasms could also trigger distal embolism from an unstable atherosclerotic plaque by creating a prothrombotic status. These distal ischemic events were the first ET manifestation and therefore lead to myeloproliferative neoplasm diagnosis. In ET, thrombosis event can occur with a normal platelet count. Furthermore, hemogram should be regularly controlled among JAK2 muted patients considering the frequent evolution from isolated JAK2 mutation to ET.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Trombose
/
Aterosclerose
/
Trombocitemia Essencial
/
Transtornos Mieloproliferativos
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Humans
Idioma:
En
Revista:
J Med Vasc
Ano de publicação:
2021
Tipo de documento:
Article