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Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase.
Amitai, Gabriel; Plotnikov, Alexander; Chapman, Shira; Lazar, Shlomi; Gez, Rellie; Loewenthal, Dan; Shurrush, Khriesto A; Cohen, Galit; Solmesky, Leonardo J; Barr, Haim; Russell, Alan J.
Afiliação
  • Amitai G; The Wohl Drug Discovery Institute, Grand Israel National Center for Personalized Medicine (G-INCPM), The Weizmann Institute of Science, Rehovot, Israel.
  • Plotnikov A; The Wohl Drug Discovery Institute, Grand Israel National Center for Personalized Medicine (G-INCPM), The Weizmann Institute of Science, Rehovot, Israel.
  • Chapman S; Department of Pharmacology, Israel Institute for Biological Research (IIBR), Ness Ziona, Israel.
  • Lazar S; Department of Pharmacology, Israel Institute for Biological Research (IIBR), Ness Ziona, Israel.
  • Gez R; Department of Pharmacology, Israel Institute for Biological Research (IIBR), Ness Ziona, Israel.
  • Loewenthal D; Department of Analytical Chemistry, IIBR, Ness Ziona, Israel.
  • Shurrush KA; The Wohl Drug Discovery Institute, Grand Israel National Center for Personalized Medicine (G-INCPM), The Weizmann Institute of Science, Rehovot, Israel.
  • Cohen G; The Wohl Drug Discovery Institute, Grand Israel National Center for Personalized Medicine (G-INCPM), The Weizmann Institute of Science, Rehovot, Israel.
  • Solmesky LJ; The Wohl Drug Discovery Institute, Grand Israel National Center for Personalized Medicine (G-INCPM), The Weizmann Institute of Science, Rehovot, Israel.
  • Barr H; The Wohl Drug Discovery Institute, Grand Israel National Center for Personalized Medicine (G-INCPM), The Weizmann Institute of Science, Rehovot, Israel.
  • Russell AJ; Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA. alanrussell@cmu.edu.
Commun Biol ; 4(1): 573, 2021 05 14.
Article em En | MEDLINE | ID: mdl-33990679

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oximas / Butirilcolinesterase / Barreira Hematoencefálica / Inibidores da Colinesterase / Agentes Neurotóxicos Limite: Animals / Humans / Male Idioma: En Revista: Commun Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Israel

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oximas / Butirilcolinesterase / Barreira Hematoencefálica / Inibidores da Colinesterase / Agentes Neurotóxicos Limite: Animals / Humans / Male Idioma: En Revista: Commun Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Israel