On the mechanism of tumor cell entry of aloe-emodin, a natural compound endowed with anticancer activity.

Pecere, Teresa; Ponterio, Eleonora; Di Iorio, Enzo; Carli, Modesto; Fassan, Matteo; Santoro, Luisa; Bissaro, Maicol; Bernabè, Giulia; Moro, Stefano; Castagliuolo, Ignazio; Palù, Giorgio

Pecere, Teresa; Ponterio, Eleonora; Di Iorio, Enzo; Carli, Modesto; Fassan, Matteo; Santoro, Luisa; Bissaro, Maicol; Bernabè, Giulia; Moro, Stefano; Castagliuolo, Ignazio; Palù, Giorgio.

Afiliação

Pecere T; Department of Molecular Medicine, University of Padova, Padova, Italy.
Ponterio E; Department of Molecular Medicine, University of Padova, Padova, Italy.
Di Iorio E; Department of Molecular Medicine, University of Padova, Padova, Italy.
Carli M; Hematology Oncology Division, Department of Women's and Children's Health, University of Padova, Padova, Italy.
Fassan M; Department of Medicine, University of Padova, Padova, Italy.
Santoro L; Azienda Ospedaliera di Padova, Padova, Italy.
Bissaro M; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
Bernabè G; Department of Molecular Medicine, University of Padova, Padova, Italy.
Moro S; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
Castagliuolo I; Department of Molecular Medicine, University of Padova, Padova, Italy.
Palù G; Department of Molecular Medicine, University of Padova, Padova, Italy.

Int J Cancer ; 149(5): 1129-1136, 2021 09 01.

Article em En | MEDLINE | ID: mdl-33990938

Assuntos

Aloe/química; Antineoplásicos Fitogênicos/farmacologia; Biomarcadores Tumorais/metabolismo; Emodina/farmacologia; Neoplasias/tratamento farmacológico; Receptores de Somatostatina/metabolismo; Apoptose; Biomarcadores Tumorais/genética; Proliferação de Células; Humanos; Neoplasias/genética; Neoplasias/metabolismo; Neoplasias/patologia; Espécies Reativas de Oxigênio/metabolismo; Receptores de Somatostatina/genética; Células Tumorais Cultivadas

Palavras-chave

aloe-emodin; anticancer activity; somatostatin receptor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Emodina / Receptores de Somatostatina / Aloe / Neoplasias / Antineoplásicos Fitogênicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Int J Cancer Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália

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