[Progress of researches on the involvement of indoleamine 2, 3-dioxygenase in regulation of parasite-host immune interactions].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
; 33(2): 209-212, 2020 Jul 21.
Article
em Zh
| MEDLINE
| ID: mdl-34008371
ABSTRACT
Indoleamine 2, 3-dioxygenase (IDO) is an important immunoregulatory enzyme, which mediates immune effects by depleting tryptophan and producing multiple metabolites. Recently, the studies on the immune function of IDO have been mostly restricted in tumors and autoimmune diseases. Nevertheless, there are few studies pertaining to the role of IDO in parasitic diseases, notably in parasite-host immune interactions. This review mainly describes IDO-mediated immunoregulatory effects and its regulation of parasite-host interactions, so as to provide insights into the development of immune intervention schemes against parasitic diseases.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Parasitos
/
Doenças Autoimunes
/
Neoplasias
Limite:
Animals
Idioma:
Zh
Revista:
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
China