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The histone H3K9M mutation synergizes with H3K14 ubiquitylation to selectively sequester histone H3K9 methyltransferase Clr4 at heterochromatin.
Shan, Chun-Min; Kim, Jin-Kwang; Wang, Jiyong; Bao, Kehan; Sun, Yadong; Chen, Huijie; Yue, Jia-Xing; Stirpe, Alessandro; Zhang, Zhiguo; Lu, Chao; Schalch, Thomas; Liti, Gianni; Nagy, Peter L; Tong, Liang; Qiao, Feng; Jia, Songtao.
Afiliação
  • Shan CM; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
  • Kim JK; Department of Biological Chemistry, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA.
  • Wang J; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
  • Bao K; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
  • Sun Y; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
  • Chen H; Department of Pathology, Columbia University, New York, NY 10068, USA.
  • Yue JX; Université Côte d'Azur, CNRS, INSERM, IRCAN, Nice 06107, France.
  • Stirpe A; Leicester Institute for Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 9HN, UK.
  • Zhang Z; Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, NY 10032, USA; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA; Department of Pediatrics, Columbia University Irving Medical Center, New York, NY 10032,
  • Lu C; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Schalch T; Leicester Institute for Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 9HN, UK.
  • Liti G; Université Côte d'Azur, CNRS, INSERM, IRCAN, Nice 06107, France.
  • Nagy PL; Department of Pathology, Columbia University, New York, NY 10068, USA.
  • Tong L; Department of Biological Sciences, Columbia University, New York, NY 10027, USA.
  • Qiao F; Department of Biological Chemistry, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA.
  • Jia S; Department of Biological Sciences, Columbia University, New York, NY 10027, USA. Electronic address: sj2274@columbia.edu.
Cell Rep ; 35(7): 109137, 2021 05 18.
Article em En | MEDLINE | ID: mdl-34010645
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Heterocromatina / Histonas / Histona-Lisina N-Metiltransferase / Proteínas de Ciclo Celular / Proteínas de Schizosaccharomyces pombe / Ubiquitinação / Histona Metiltransferases Idioma: En Revista: Cell Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Heterocromatina / Histonas / Histona-Lisina N-Metiltransferase / Proteínas de Ciclo Celular / Proteínas de Schizosaccharomyces pombe / Ubiquitinação / Histona Metiltransferases Idioma: En Revista: Cell Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos