A mTORC1-mediated cyst(e)ine sensing mechanism governing GPX4 synthesis and ferroptosis.

Yan, Yuelong; Lei, Guang; Gan, Boyi

Yan, Yuelong; Lei, Guang; Gan, Boyi.

Afiliação

Yan Y; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Lei G; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Gan B; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Mol Cell Oncol ; 8(3): 1919006, 2021.

Article em En | MEDLINE | ID: mdl-34027051

Palavras-chave

GPX4; SLC7A11; cancer therapy; cysteine; cystine; ferroptosis; lipid peroxidation; mTORC1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Mol Cell Oncol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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