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Water-soluble derivatives of evodiamine: Discovery of evodiamine-10-phosphate as an orally active antitumor lead compound.
Chen, Shuqiang; Bi, Kaijian; Wu, Shanchao; Li, Yu; Huang, Yahui; Sheng, Chunquan; Dong, Guoqiang.
Afiliação
  • Chen S; Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China.
  • Bi K; Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China.
  • Wu S; Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China.
  • Li Y; Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China.
  • Huang Y; Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China.
  • Sheng C; Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China. Electronic address: shengcq@smmu.edu.cn.
  • Dong G; Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China. Electronic address: dgq-81@163.com.
Eur J Med Chem ; 220: 113544, 2021 Aug 05.
Article em En | MEDLINE | ID: mdl-34052678

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatos / Quinazolinas / Descoberta de Drogas / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatos / Quinazolinas / Descoberta de Drogas / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article