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Targeting the Microtubule EB1-CLASP2 Complex Modulates NaV1.5 at Intercalated Discs.
Marchal, Gerard A; Jouni, Mariam; Chiang, David Y; Pérez-Hernández, Marta; Podliesna, Svitlana; Yu, Nuo; Casini, Simona; Potet, Franck; Veerman, Christiaan C; Klerk, Mischa; Lodder, Elisabeth M; Mengarelli, Isabella; Guan, Kaomei; Vanoye, Carlos G; Rothenberg, Eli; Charpentier, Flavien; Redon, Richard; George, Alfred L; Verkerk, Arie O; Bezzina, Connie R; MacRae, Calum A; Burridge, Paul W; Delmar, Mario; Galjart, Niels; Portero, Vincent; Remme, Carol Ann.
Afiliação
  • Marchal GA; Department of Experimental Cardiology, Amsterdam UMC - location AMC, The Netherlands (G.A.M., S.P., S.C., C.C.V., E.M.L., I.M., A.O.V., C.R.B., V.P., C.A.R.).
  • Jouni M; Department of Pharmacology, University Feinberg School of Medicine, Chicago, IL (M.J., F.P., C.G.V., A.L.G., P.W.B.).
  • Chiang DY; Brigham and Women's Hospital and Harvard Medical School, Boston, MA (D.Y.C., C.A.M.).
  • Pérez-Hernández M; Division of Cardiology (M.P.-H., M.D.), NYU School of Medicine.
  • Podliesna S; Department of Experimental Cardiology, Amsterdam UMC - location AMC, The Netherlands (G.A.M., S.P., S.C., C.C.V., E.M.L., I.M., A.O.V., C.R.B., V.P., C.A.R.).
  • Yu N; Department of Cell Biology, Erasmus Medical Centre Rotterdam, The Netherlands (N.Y., N.G.).
  • Casini S; Department of Experimental Cardiology, Amsterdam UMC - location AMC, The Netherlands (G.A.M., S.P., S.C., C.C.V., E.M.L., I.M., A.O.V., C.R.B., V.P., C.A.R.).
  • Potet F; Department of Pharmacology, University Feinberg School of Medicine, Chicago, IL (M.J., F.P., C.G.V., A.L.G., P.W.B.).
  • Veerman CC; Department of Experimental Cardiology, Amsterdam UMC - location AMC, The Netherlands (G.A.M., S.P., S.C., C.C.V., E.M.L., I.M., A.O.V., C.R.B., V.P., C.A.R.).
  • Klerk M; Department of Medical Biology, Amsterdam UMC - location AMC, The Netherlands (M.K., A.O.V.).
  • Lodder EM; Department of Experimental Cardiology, Amsterdam UMC - location AMC, The Netherlands (G.A.M., S.P., S.C., C.C.V., E.M.L., I.M., A.O.V., C.R.B., V.P., C.A.R.).
  • Mengarelli I; Department of Experimental Cardiology, Amsterdam UMC - location AMC, The Netherlands (G.A.M., S.P., S.C., C.C.V., E.M.L., I.M., A.O.V., C.R.B., V.P., C.A.R.).
  • Guan K; Institute of Pharmacology and Toxicology, Technische Universität Dresden, Germany (K.G.).
  • Vanoye CG; Department of Pharmacology, University Feinberg School of Medicine, Chicago, IL (M.J., F.P., C.G.V., A.L.G., P.W.B.).
  • Rothenberg E; Department of Biochemistry and Pharmacology (E.R.), NYU School of Medicine.
  • Charpentier F; Université de Nantes, CNRS, INSERM, l'institut du Thorax, Nantes, France (F.C., R.R., V.P.).
  • Redon R; Université de Nantes, CNRS, INSERM, l'institut du Thorax, Nantes, France (F.C., R.R., V.P.).
  • George AL; Department of Pharmacology, University Feinberg School of Medicine, Chicago, IL (M.J., F.P., C.G.V., A.L.G., P.W.B.).
  • Verkerk AO; Department of Experimental Cardiology, Amsterdam UMC - location AMC, The Netherlands (G.A.M., S.P., S.C., C.C.V., E.M.L., I.M., A.O.V., C.R.B., V.P., C.A.R.).
  • Bezzina CR; Department of Medical Biology, Amsterdam UMC - location AMC, The Netherlands (M.K., A.O.V.).
  • MacRae CA; Department of Experimental Cardiology, Amsterdam UMC - location AMC, The Netherlands (G.A.M., S.P., S.C., C.C.V., E.M.L., I.M., A.O.V., C.R.B., V.P., C.A.R.).
  • Burridge PW; Brigham and Women's Hospital and Harvard Medical School, Boston, MA (D.Y.C., C.A.M.).
  • Delmar M; Department of Pharmacology, University Feinberg School of Medicine, Chicago, IL (M.J., F.P., C.G.V., A.L.G., P.W.B.).
  • Galjart N; Division of Cardiology (M.P.-H., M.D.), NYU School of Medicine.
  • Portero V; Department of Cell Biology, Erasmus Medical Centre Rotterdam, The Netherlands (N.Y., N.G.).
  • Remme CA; Department of Experimental Cardiology, Amsterdam UMC - location AMC, The Netherlands (G.A.M., S.P., S.C., C.C.V., E.M.L., I.M., A.O.V., C.R.B., V.P., C.A.R.).
Circ Res ; 129(3): 349-365, 2021 07 23.
Article em En | MEDLINE | ID: mdl-34092082
ABSTRACT
[Figure see text].
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Miócitos Cardíacos / Canal de Sódio Disparado por Voltagem NAV1.5 / Proteínas Associadas aos Microtúbulos Limite: Animals / Humans / Male Idioma: En Revista: Circ Res Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Miócitos Cardíacos / Canal de Sódio Disparado por Voltagem NAV1.5 / Proteínas Associadas aos Microtúbulos Limite: Animals / Humans / Male Idioma: En Revista: Circ Res Ano de publicação: 2021 Tipo de documento: Article