Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC).
J Cell Physiol
; 236(12): 8137-8147, 2021 12.
Article
em En
| MEDLINE
| ID: mdl-34133753
ABSTRACT
Thiazolidinediones are synthetic PPARγ ligands that enhance insulin sensitivity, and that could increase insulin secretion from ß-cells. However, the functional role and mechanism(s) of action in pancreatic ß-cells have not been investigated in detail.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Adenilil Ciclases
/
Tiazolidinedionas
/
Células Secretoras de Insulina
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Secreção de Insulina
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Cell Physiol
Ano de publicação:
2021
Tipo de documento:
Article