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An ACE2 Triple Decoy that neutralizes SARS-CoV-2 shows enhanced affinity for virus variants.
Tanaka, Shiho; Nelson, Gard; Olson, C Anders; Buzko, Oleksandr; Higashide, Wendy; Shin, Annie; Gonzalez, Marcos; Taft, Justin; Patel, Roosheel; Buta, Sofija; Richardson, Ashley; Bogunovic, Dusan; Spilman, Patricia; Niazi, Kayvan; Rabizadeh, Shahrooz; Soon-Shiong, Patrick.
Afiliação
  • Tanaka S; ImmunityBio, Inc., 9920 Jefferson Blvd., Culver City, CA, 90232, USA. Shiho.tanaka@immunitybio.com.
  • Nelson G; ImmunityBio, Inc., 9920 Jefferson Blvd., Culver City, CA, 90232, USA.
  • Olson CA; ImmunityBio, Inc., 9920 Jefferson Blvd., Culver City, CA, 90232, USA.
  • Buzko O; ImmunityBio, Inc., 9920 Jefferson Blvd., Culver City, CA, 90232, USA.
  • Higashide W; ImmunityBio, Inc., 9920 Jefferson Blvd., Culver City, CA, 90232, USA.
  • Shin A; ImmunityBio, Inc., 9920 Jefferson Blvd., Culver City, CA, 90232, USA.
  • Gonzalez M; ImmunityBio, Inc., 9920 Jefferson Blvd., Culver City, CA, 90232, USA.
  • Taft J; Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, 1 Gustave Lane, Levy Place, New York, NY, 10029-5674, USA.
  • Patel R; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave Lane, Levy Place, New York, NY, 10029-5674, USA.
  • Buta S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, 1 Gustave Lane, Levy Place, New York, NY, 10029-5674, USA.
  • Richardson A; Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, 1 Gustave Lane, Levy Place, New York, NY, 10029-5674, USA.
  • Bogunovic D; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, 1 Gustave Lane, Levy Place, New York, NY, 10029-5674, USA.
  • Spilman P; Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, 1 Gustave Lane, Levy Place, New York, NY, 10029-5674, USA.
  • Niazi K; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, 1 Gustave Lane, Levy Place, New York, NY, 10029-5674, USA.
  • Rabizadeh S; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave Lane, Levy Place, New York, NY, 10029-5674, USA.
  • Soon-Shiong P; Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, 1 Gustave Lane, Levy Place, New York, NY, 10029-5674, USA.
Sci Rep ; 11(1): 12740, 2021 06 17.
Article em En | MEDLINE | ID: mdl-34140558
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Transdução de Sinais / Substituição de Aminoácidos / Descoberta de Drogas / Simulação de Dinâmica Molecular / Enzima de Conversão de Angiotensina 2 / SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Transdução de Sinais / Substituição de Aminoácidos / Descoberta de Drogas / Simulação de Dinâmica Molecular / Enzima de Conversão de Angiotensina 2 / SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos