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Design, Synthesis and In-Vitro Biological Evaluation of Antofine and Tylophorine Prodrugs as Hypoxia-Targeted Anticancer Agents.
Omran, Ziad; Guise, Chris P; Chen, Linwei; Rauch, Cyril; Abdalla, Ashraf N; Abdullah, Omeima; Sindi, Ikhlas A; Fischer, Peter M; Smaill, Jeff B; Patterson, Adam V; Liu, Yuxiu; Wang, Qingmin.
Afiliação
  • Omran Z; Department of Pharmaceutical Sciences, Pharmacy Department, Batterjee Medical College, Jeddah 21442, Saudi Arabia.
  • Guise CP; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Chen L; State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China.
  • Rauch C; School of Veterinary Medicine and Science, University of Nottingham, College Road, Sutton Bonington LE12 5RD, UK.
  • Abdalla AN; College of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
  • Abdullah O; College of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
  • Sindi IA; Department of Biology, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
  • Fischer PM; School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UK.
  • Smaill JB; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Patterson AV; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Liu Y; State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China.
  • Wang Q; State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China.
Molecules ; 26(11)2021 Jun 01.
Article em En | MEDLINE | ID: mdl-34206005
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenantrenos / Fenantrolinas / Pró-Fármacos / Alcaloides / Hipóxia Tumoral / Compostos de Amônio Quaternário / Indóis / Indolizinas / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Arábia Saudita
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenantrenos / Fenantrolinas / Pró-Fármacos / Alcaloides / Hipóxia Tumoral / Compostos de Amônio Quaternário / Indóis / Indolizinas / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Arábia Saudita