Protein Amyloid Cofactors: Charged Side-Chain Arrays Meet Their Match?
Trends Biochem Sci
; 46(8): 626-629, 2021 08.
Article
em En
| MEDLINE
| ID: mdl-34210544
ABSTRACT
Recent advances in high-resolution structural studies of protein amyloids have revealed parallel in-register cross-ß-sheets with periodic arrays of closely spaced identical residues. What do these structures tell us about the mechanisms of action of common amyloid-promoting factors, such as heparan sulfate (HS), nucleic acids, polyphosphates, anionic phospholipids, and acidic pH?
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Amiloide
Idioma:
En
Revista:
Trends Biochem Sci
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Estados Unidos