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A Mammalian Target of Rapamycin-Perilipin 3 (mTORC1-Plin3) Pathway is essential to Activate Lipophagy and Protects Against Hepatosteatosis.
Garcia-Macia, Marina; Santos-Ledo, Adrián; Leslie, Jack; Paish, Hannah L; Collins, Amy L; Scott, Rebecca S; Watson, Abigail; Burgoyne, Rachel A; White, Steve; French, Jeremy; Hammond, John; Borthwick, Lee A; Mann, Jelena; Bolaños, Juan P; Korolchuk, Viktor I; Oakley, Fiona; Mann, Derek A.
Afiliação
  • Garcia-Macia M; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Santos-Ledo A; Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, Salamanca, Spain.
  • Leslie J; Institute of Functional Biology and Genomics, University of Salamanca, CSIC, Salamanca, Spain.
  • Paish HL; Centro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.
  • Collins AL; E.U.E Dacio Crespo (Universidad de Valladolid), Palencia, Spain.
  • Scott RS; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Watson A; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Burgoyne RA; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • White S; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • French J; FibroFind Ltd, William Leech Building, Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Hammond J; FibroFind Ltd, William Leech Building, Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Borthwick LA; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Mann J; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
  • Bolaños JP; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
  • Korolchuk VI; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
  • Oakley F; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Mann DA; Newcastle Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Hepatology ; 74(6): 3441-3459, 2021 12.
Article em En | MEDLINE | ID: mdl-34233024
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Transdução de Sinais / Hepatócitos / Fígado Gorduroso / Perilipina-3 / Alvo Mecanístico do Complexo 1 de Rapamicina Limite: Animals / Humans / Male Idioma: En Revista: Hepatology Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Transdução de Sinais / Hepatócitos / Fígado Gorduroso / Perilipina-3 / Alvo Mecanístico do Complexo 1 de Rapamicina Limite: Animals / Humans / Male Idioma: En Revista: Hepatology Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido