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Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial.
Arabi, Yaseen M; Gordon, Anthony C; Derde, Lennie P G; Nichol, Alistair D; Murthy, Srinivas; Beidh, Farah Al; Annane, Djillali; Swaidan, Lolowa Al; Beane, Abi; Beasley, Richard; Berry, Lindsay R; Bhimani, Zahra; Bonten, Marc J M; Bradbury, Charlotte A; Brunkhorst, Frank M; Buxton, Meredith; Buzgau, Adrian; Cheng, Allen; De Jong, Menno; Detry, Michelle A; Duffy, Eamon J; Estcourt, Lise J; Fitzgerald, Mark; Fowler, Rob; Girard, Timothy D; Goligher, Ewan C; Goossens, Herman; Haniffa, Rashan; Higgins, Alisa M; Hills, Thomas E; Horvat, Christopher M; Huang, David T; King, Andrew J; Lamontagne, Francois; Lawler, Patrick R; Lewis, Roger; Linstrum, Kelsey; Litton, Edward; Lorenzi, Elizabeth; Malakouti, Salim; McAuley, Daniel F; McGlothlin, Anna; Mcguinness, Shay; McVerry, Bryan J; Montgomery, Stephanie K; Morpeth, Susan C; Mouncey, Paul R; Orr, Katrina; Parke, Rachael; Parker, Jane C.
Afiliação
  • Arabi YM; Intensive Care Department, Ministry of the National Guard-Health Affairs, ICU 1425, P.O. Box 22490, Riyadh, 11426, Kingdom of Saudi Arabia. arabi@ngha.med.sa.
  • Gordon AC; King Abdullah International Medical Research Center, Riyadh, Kingdom of Saudi Arabia. arabi@ngha.med.sa.
  • Derde LPG; King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia. arabi@ngha.med.sa.
  • Nichol AD; Division of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, London, UK.
  • Murthy S; Intensive Care Unit, Imperial College Healthcare NHS Trust, London, UK.
  • Beidh FA; Intensive Care Center, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Annane D; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Swaidan LA; University College Dublin Clinical Research Centre At St Vincents University Hospital, Dublin, Ireland.
  • Beane A; The Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia.
  • Beasley R; The Alfred Hospital, Melbourne, Australia.
  • Berry LR; Department of Pediatrics, University of British Columbia, Vancouver, Canada.
  • Bhimani Z; Division of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, London, UK.
  • Bonten MJM; Department of Intensive Care, Hôpital Raymond Poincaré (APHP), 92380, Garches, France.
  • Bradbury CA; Laboratory of Infection and Inflammation, U1173, School of Medicine Simone Veil, University Versailles Saint Quentin and University Paris Saclay, INSERM, 78423, Montigny le Bretonneux, France.
  • Brunkhorst FM; FHU SEPSIS (Saclay and Paris Seine Nord Endeavour To PerSonalize Interventions for Sepsis) and RHU RECORDS (Rapid rEcognition of CORticosteroiD Resistant Or Sensitive Sepsis), ANR-18-RHUS60004, 92380, Garches, France.
  • Buxton M; King Abdullah International Medical Research Center, Riyadh, Kingdom of Saudi Arabia.
  • Buzgau A; King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
  • Cheng A; Pharmaceutical Care Services, Ministry of National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia.
  • De Jong M; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
  • Detry MA; Medical Research Institute of New Zealand, Wellington, New Zealand.
  • Duffy EJ; Berry Consultants, Austin, TX, USA.
  • Estcourt LJ; St. Michael's Hospital Unity Health Toronto, Toronto, Canada.
  • Fitzgerald M; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Fowler R; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Girard TD; Faculty of Health Sciences, University of Bristol, Bristol, UK.
  • Goligher EC; Bristol Hematology and Oncology Centre, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
  • Goossens H; Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.
  • Haniffa R; Global Coalition for Adaptive Research, San Francisco, CA, USA.
  • Higgins AM; Monash University, Melbourne, Australia.
  • Hills TE; Monash University, Melbourne, Australia.
  • Horvat CM; Department of Infectious Diseases, Alfred Health, Melbourne, Australia.
  • Huang DT; Department of Medical Microbiology and Infection Prevention, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • King AJ; Berry Consultants, Austin, TX, USA.
  • Lamontagne F; Infectious Disease, Auckland City Hospital, Auckland, New Zealand.
  • Lawler PR; NHS Blood and Transplant, Oxford, UK.
  • Lewis R; Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Linstrum K; Berry Consultants, Austin, TX, USA.
  • Litton E; University of Toronto, Toronto, ON, Canada.
  • Lorenzi E; Sunnybrook Health Sciences Centre, Toronto, Canada.
  • Malakouti S; Canadian Critical Care Trials Group, Toronto, Canada.
  • McAuley DF; UPMC Health System, Pittsburgh, PA, USA.
  • McGlothlin A; University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Mcguinness S; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.
  • McVerry BJ; University of Antwerp, Wilrijk, Belgium.
  • Montgomery SK; National Intensive Care Surveillance-Mahidol Oxford Research Unit, Colombo, Sri Lanka.
  • Morpeth SC; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
  • Mouncey PR; Critical Care Department, University College Hospital, London, UK.
  • Orr K; The Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia.
  • Parke R; Medical Research Institute of New Zealand, Wellington, New Zealand.
  • Parker JC; Auckland District Health Board, Auckland, New Zealand.
Intensive Care Med ; 47(8): 867-886, 2021 Aug.
Article em En | MEDLINE | ID: mdl-34251506
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ritonavir / Tratamento Farmacológico da COVID-19 Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Humans Idioma: En Revista: Intensive Care Med Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ritonavir / Tratamento Farmacológico da COVID-19 Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Humans Idioma: En Revista: Intensive Care Med Ano de publicação: 2021 Tipo de documento: Article