The E3 Ubiquitin Ligase Ring Finger Protein 5 Ameliorates NASH Through Ubiquitin-Mediated Degradation of 3-Hydroxy-3-Methylglutaryl CoA Reductase Degradation Protein 1.

Yang, Qin; Chen, Xi; Zhang, Yanfang; Hu, Sha; Hu, Fengjiao; Huang, Yongping; Ma, Tengfei; Hu, Heng; Tian, Han; Tian, Song; Ji, Yan-Xiao; She, Zhi-Gang; Zhang, Peng; Zhang, Xiao-Jing; Hu, Yufeng; Yang, Hailong; Yuan, Yufeng; Li, Hongliang

Yang, Qin; Chen, Xi; Zhang, Yanfang; Hu, Sha; Hu, Fengjiao; Huang, Yongping; Ma, Tengfei; Hu, Heng; Tian, Han; Tian, Song; Ji, Yan-Xiao; She, Zhi-Gang; Zhang, Peng; Zhang, Xiao-Jing; Hu, Yufeng; Yang, Hailong; Yuan, Yufeng; Li, Hongliang.

Afiliação

Yang Q; Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.
Chen X; Institute of Model Animal of Wuhan University, Wuhan, China.
Zhang Y; Medical Science Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
Hu S; Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.
Hu F; Clinical Medicine Research Center for Minimally Invasive Procedures of Hepatobiliary and Pancreatic Diseases of Hubei Province, Hubei, China.
Huang Y; Institute of Model Animal of Wuhan University, Wuhan, China.
Ma T; School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Hu H; Institute of Model Animal of Wuhan University, Wuhan, China.
Tian H; Institute of Model Animal of Wuhan University, Wuhan, China.
Tian S; Medical Science Research Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
Ji YX; Institute of Model Animal of Wuhan University, Wuhan, China.
She ZG; Institute of Model Animal of Wuhan University, Wuhan, China.
Zhang P; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Zhang XJ; Institute of Model Animal of Wuhan University, Wuhan, China.
Hu Y; Institute of Model Animal of Wuhan University, Wuhan, China.
Yang H; Institute of Model Animal of Wuhan University, Wuhan, China.
Yuan Y; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Li H; Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.

Hepatology ; 74(6): 3018-3036, 2021 12.

Article em En | MEDLINE | ID: mdl-34272738

Assuntos

Proteínas de Ligação a DNA/metabolismo; Proteínas de Membrana/metabolismo; Hepatopatia Gordurosa não Alcoólica/patologia; Ubiquitina-Proteína Ligases/metabolismo; Animais; Biópsia; Proteínas de Ligação a DNA/análise; Dieta Hiperlipídica/efeitos adversos; Modelos Animais de Doenças; Regulação para Baixo; Feminino; Técnicas de Silenciamento de Genes; Células HEK293; Hepatócitos; Humanos; Fígado/patologia; Masculino; Proteínas de Membrana/análise; Camundongos; Cultura Primária de Células; Mapeamento de Interação de Proteínas; Proteólise; RNA-Seq; Ubiquitina-Proteína Ligases/análise; Ubiquitina-Proteína Ligases/genética; Ubiquitinação

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ubiquitina-Proteína Ligases / Proteínas de Ligação a DNA / Hepatopatia Gordurosa não Alcoólica / Proteínas de Membrana Limite: Animals / Female / Humans / Male Idioma: En Revista: Hepatology Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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