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GSK137, a potent small-molecule BCL6 inhibitor with in vivo activity, suppresses antibody responses in mice.
Pearce, Andrew C; Bamford, Mark J; Barber, Ruth; Bridges, Angela; Convery, Maire A; Demetriou, Constantinos; Evans, Sian; Gobbetti, Thomas; Hirst, David J; Holmes, Duncan S; Hutchinson, Jonathan P; Jayne, Sandrine; Lezina, Larissa; McCabe, Michael T; Messenger, Cassie; Morley, Joanne; Musso, Melissa C; Scott-Stevens, Paul; Manso, Ana Sousa; Schofield, Jennifer; Slocombe, Tom; Somers, Don; Walker, Ann L; Wyce, Anastasia; Zhang, Xi-Ping; Wagner, Simon D.
Afiliação
  • Pearce AC; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Bamford MJ; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Barber R; Leicester Drug Discovery and Diagnostics, University of Leicester, Leicester, UK.
  • Bridges A; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Convery MA; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Demetriou C; Leicester Cancer Research Centre and Ernest and Helen Scott Haematological Research Unit, University of Leicester, Leicester, UK.
  • Evans S; Leicester Drug Discovery and Diagnostics, University of Leicester, Leicester, UK.
  • Gobbetti T; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Hirst DJ; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Holmes DS; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Hutchinson JP; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Jayne S; Leicester Cancer Research Centre and Ernest and Helen Scott Haematological Research Unit, University of Leicester, Leicester, UK.
  • Lezina L; Leicester Drug Discovery and Diagnostics, University of Leicester, Leicester, UK; Leicester Cancer Research Centre and Ernest and Helen Scott Haematological Research Unit, University of Leicester, Leicester, UK.
  • McCabe MT; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Messenger C; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Morley J; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Musso MC; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Scott-Stevens P; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Manso AS; Leicester Drug Discovery and Diagnostics, University of Leicester, Leicester, UK; Leicester Cancer Research Centre and Ernest and Helen Scott Haematological Research Unit, University of Leicester, Leicester, UK.
  • Schofield J; Leicester Drug Discovery and Diagnostics, University of Leicester, Leicester, UK.
  • Slocombe T; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Somers D; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Walker AL; GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.
  • Wyce A; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Zhang XP; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Wagner SD; Leicester Cancer Research Centre and Ernest and Helen Scott Haematological Research Unit, University of Leicester, Leicester, UK. Electronic address: sw227@le.ac.uk.
J Biol Chem ; 297(2): 100928, 2021 08.
Article em En | MEDLINE | ID: mdl-34274316
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-bcl-6 Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-bcl-6 Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido