Neuronal activity-induced SUMOylation of Akt1 by PIAS3 is required for long-term potentiation of synaptic transmission.

Meng, Li; Du, Cai-Ping; Lu, Chun-Yuan; Zhang, Kun; Li, Lin; Yan, Jing-Zhi; Hou, Xiao-Yu

Meng, Li; Du, Cai-Ping; Lu, Chun-Yuan; Zhang, Kun; Li, Lin; Yan, Jing-Zhi; Hou, Xiao-Yu.

Afiliação

Meng L; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.
Du CP; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.
Lu CY; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.
Zhang K; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.
Li L; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.
Yan JZ; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.
Hou XY; Jiangsu Key Laboratory of Brain Disease Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, China.

FASEB J ; 35(8): e21769, 2021 08.

Article em En | MEDLINE | ID: mdl-34288124

Assuntos

Hipocampo; Chaperonas Moleculares/metabolismo; Neurônios; Proteínas Inibidoras de STAT Ativados/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transmissão Sináptica; Animais; Células Cultivadas; Feminino; Células HEK293; Hipocampo/citologia; Hipocampo/metabolismo; Humanos; Masculino; Neurônios/citologia; Neurônios/metabolismo; Fosforilação; Cultura Primária de Células; Ratos; Ratos Sprague-Dawley; Sumoilação

Palavras-chave

Akt1; ERK1/2 signaling; SUMO1 conjugation; brain-derived neurotrophic factor; synaptic plasticity

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transmissão Sináptica / Chaperonas Moleculares / Proteínas Proto-Oncogênicas c-akt / Proteínas Inibidoras de STAT Ativados / Hipocampo / Neurônios Limite: Animals / Female / Humans / Male Idioma: En Revista: FASEB J Assunto da revista: BIOLOGIA / FISIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google