Caveolin-1 increases glycolysis in pancreatic cancer cells and triggers cachectic states.

Hu, Lijuan; Xu, Xiaoqing; Li, Qiuju; Chen, Xijuan; Yuan, Xiangfei; Qiu, Shuai; Yao, Chuanshan; Zhang, Dapeng; Wang, Feng

Hu, Lijuan; Xu, Xiaoqing; Li, Qiuju; Chen, Xijuan; Yuan, Xiangfei; Qiu, Shuai; Yao, Chuanshan; Zhang, Dapeng; Wang, Feng.

Afiliação

Hu L; The Laboratory of Acute Abdomen Disease Associated Organ Injury and Repair, Nankai Hospital Affiliated to Nankai University, Tianjin, China.
Xu X; The Graduate School, Tianjin Medical University, Tianjin, China.
Li Q; The Graduate School, Tianjin Medical University, Tianjin, China.
Chen X; The Graduate School, Tianjin Medical University, Tianjin, China.
Yuan X; The Laboratory of Acute Abdomen Disease Associated Organ Injury and Repair, Nankai Hospital Affiliated to Nankai University, Tianjin, China.
Qiu S; The Graduate School, Tianjin Medical University, Tianjin, China.
Yao C; The Medical School, Nankai University, Tianjin, China.
Zhang D; The Laboratory of Acute Abdomen Disease Associated Organ Injury and Repair, Nankai Hospital Affiliated to Nankai University, Tianjin, China.
Wang F; The Laboratory of Acute Abdomen Disease Associated Organ Injury and Repair, Nankai Hospital Affiliated to Nankai University, Tianjin, China.

FASEB J ; 35(8): e21826, 2021 08.

Article em En | MEDLINE | ID: mdl-34320244

Assuntos

Caquexia/etiologia; Caveolina 1/metabolismo; Glicólise/fisiologia; Neoplasias Pancreáticas/metabolismo; Receptor IGF Tipo 1/metabolismo; Receptor de Insulina/metabolismo; Animais; Caveolina 1/genética; Linhagem Celular Tumoral; Deleção de Genes; Regulação da Expressão Gênica/fisiologia; Humanos; Camundongos; Camundongos Nus; Neoplasias Experimentais/metabolismo; Receptor IGF Tipo 1/genética; Receptor de Insulina/genética

Palavras-chave

cancer cachexia; caveolin-1; glycolysis; pancreatic cancer

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Caquexia / Receptor de Insulina / Receptor IGF Tipo 1 / Caveolina 1 / Glicólise Limite: Animals / Humans Idioma: En Revista: FASEB J Assunto da revista: BIOLOGIA / FISIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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