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Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro.
Mossink, Britt; Verboven, Anouk H A; van Hugte, Eline J H; Klein Gunnewiek, Teun M; Parodi, Giulia; Linda, Katrin; Schoenmaker, Chantal; Kleefstra, Tjitske; Kozicz, Tamas; van Bokhoven, Hans; Schubert, Dirk; Nadif Kasri, Nael; Frega, Monica.
Afiliação
  • Mossink B; Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands; Department of Clinical Neurophysiology, University of Twente, 7522 NB Enschede, the Netherlands.
  • Verboven AHA; Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands; Centre for Molecular and Biomolecular Informatics, Radboudumc, Radboud Institute for Molecular Life Sciences, 6500 HB Nijmegen, the Netherlands.
  • van Hugte EJH; Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands; ACE Kempenhaeghe, Department of Epileptology, 5591 VE Heeze, the Netherlands.
  • Klein Gunnewiek TM; Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands; Department of Medical Imaging, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Parodi G; Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands.
  • Linda K; Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands.
  • Schoenmaker C; Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands.
  • Kleefstra T; Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands.
  • Kozicz T; Department of Medical Imaging, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA; Department of Clinical Genomics, Mayo Clinic, Rochester, MN 55905, USA.
  • van Bokhoven H; Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands; Department of Cognitive Neuroscience, Radboudumc, Donders Institute for Brain, Cognition and Behavior, 6500 HB Nijmegen, the Netherlands.
  • Schubert D; Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands; Department of Cognitive Neuroscience, Radboudumc, Donders Institute for Brain, Cognition and Behavior, 6500 HB Nijmegen, the Netherlands.
  • Nadif Kasri N; Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands; Department of Cognitive Neuroscience, Radboudumc, Donders Institute for Brain, Cognition and Behavior, 6500 HB Nijmegen, the Netherlands.
  • Frega M; Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands; Department of Clinical Genomics, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: m.frega@utwente.nl.
Stem Cell Reports ; 16(9): 2182-2196, 2021 09 14.
Article em En | MEDLINE | ID: mdl-34329594

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas de Cultura de Células / Análise em Microsséries / Eletrodos / Estudos de Associação Genética / Dispositivos Lab-On-A-Chip / Neurônios Limite: Animals / Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas de Cultura de Células / Análise em Microsséries / Eletrodos / Estudos de Associação Genética / Dispositivos Lab-On-A-Chip / Neurônios Limite: Animals / Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda