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Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2).
Lee, Lung-Chun; Peng, Yi-Hui; Chang, Hsin-Huei; Hsu, Tsu; Lu, Cheng-Tai; Huang, Chih-Hsiang; Hsueh, Ching-Cheng; Kung, Fang-Chun; Kuo, Ching-Chuan; Jiaang, Weir-Torn; Wu, Su-Ying.
Afiliação
  • Lee LC; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350 Taiwan, ROC.
  • Peng YH; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350 Taiwan, ROC.
  • Chang HH; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350 Taiwan, ROC.
  • Hsu T; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350 Taiwan, ROC.
  • Lu CT; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350 Taiwan, ROC.
  • Huang CH; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350 Taiwan, ROC.
  • Hsueh CC; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350 Taiwan, ROC.
  • Kung FC; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350 Taiwan, ROC.
  • Kuo CC; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350 Taiwan, ROC.
  • Jiaang WT; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 406, Taiwan, ROC.
  • Wu SY; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350 Taiwan, ROC.
J Med Chem ; 64(15): 11288-11301, 2021 08 12.
Article em En | MEDLINE | ID: mdl-34337952
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Xantina / Inibidores Enzimáticos / Enzimas Multifuncionais / Aminoidrolases / Metilenotetra-Hidrofolato Desidrogenase (NADP) Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Xantina / Inibidores Enzimáticos / Enzimas Multifuncionais / Aminoidrolases / Metilenotetra-Hidrofolato Desidrogenase (NADP) Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article