A phosphoproteomics study reveals a defined genetic program for neural lineage commitment of neural stem cells induced by olfactory ensheathing cell-conditioned medium.

Ge, Lite; Zhang, Cheng; Xie, Huali; Zhuo, Yi; Xun, Chengfeng; Chen, Ping; Hu, Zhiping; Lu, Ming

Ge, Lite; Zhang, Cheng; Xie, Huali; Zhuo, Yi; Xun, Chengfeng; Chen, Ping; Hu, Zhiping; Lu, Ming.

Afiliação

Ge L; The National & Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha 410006, PR China; Department of Neurology, Second Xiangya Hospital, Central South University, Changsha 410011, PR China; Hunan Provincical Key Laborat
Zhang C; The National & Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha 410006, PR China; Guangdong Provincial Key Laboratory of Biotechnology for Plant Development, School of Life Science, South China Normal University, G
Xie H; The National & Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha 410006, PR China.
Zhuo Y; The National & Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha 410006, PR China; Hunan Provincical Key Laboratory of Neurorestoratology, The Second Affiliated Hospital, Hunan Normal University, Changsha 410003, PR
Xun C; The National & Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha 410006, PR China.
Chen P; The National & Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha 410006, PR China. Electronic address: chenp@hunnu.edu.cn.
Hu Z; Department of Neurology, Second Xiangya Hospital, Central South University, Changsha 410011, PR China. Electronic address: zhipinghu@csu.edu.cn.
Lu M; The National & Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha 410006, PR China; Hunan Provincical Key Laboratory of Neurorestoratology, The Second Affiliated Hospital, Hunan Normal University, Changsha 410003, PR

Pharmacol Res ; 172: 105797, 2021 10.

Article em En | MEDLINE | ID: mdl-34352399

Assuntos

Células-Tronco Neurais/metabolismo; Neuroglia; Bulbo Olfatório/citologia; Fosfoproteínas/genética; Proteoma/genética; Animais; Diferenciação Celular; Células Cultivadas; Meios de Cultivo Condicionados; Camundongos; Fosfoproteínas/metabolismo; Fosforilação; Mapas de Interação de Proteínas; Proteômica

Palavras-chave

Acetonitrile (PubChem CID:6342); Ammonium persulfate (PubChem CID: 62648); Differentiation; Dimethyl sulfoxide (PubChem CID: 679); Dithiothreitol (PubChem CID: 446094); Formic acid (PubChem CID: 284); Glycine (PubChem CID: 750); Iodoacetamide (PubChem CID: 3727); N,N,N',N'-Tetra(o-methylbenzyl)ethylene diamine (PubChem CID: 86028064); Neural stem cells; Olfactory ensheathing cells; Phosphoproteome; Transforming growth factor ß3; Tris-hydroxymethyl-methyl-ammonium (PubChem CID: 4468930); Urea (PubChem CID:1176)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bulbo Olfatório / Fosfoproteínas / Neuroglia / Proteoma / Células-Tronco Neurais Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article

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