Use of proteomics to identify mechanisms of hepatocellular carcinoma with the CYP2D6*10 polymorphism and identification of ANGPTL6 as a new diagnostic and prognostic biomarker.

Hu, Guiming; Gao, Fei; Wang, Guanzhe; Fang, Yan; Guo, Yuanyuan; Zhou, Jun; Gu, Yuhan; Zhang, Cunzhen; Gao, Na; Wen, Qiang; Qiao, Hailing

Hu, Guiming; Gao, Fei; Wang, Guanzhe; Fang, Yan; Guo, Yuanyuan; Zhou, Jun; Gu, Yuhan; Zhang, Cunzhen; Gao, Na; Wen, Qiang; Qiao, Hailing.

Afiliação

Hu G; Institute of Clinical Pharmacology, Zhengzhou University, Zhengzhou, 450052, Henan, China.
Gao F; Institute of Clinical Pharmacology, Zhengzhou University, Zhengzhou, 450052, Henan, China.
Wang G; Institute of Clinical Pharmacology, Zhengzhou University, Zhengzhou, 450052, Henan, China.
Fang Y; Institute of Clinical Pharmacology, Zhengzhou University, Zhengzhou, 450052, Henan, China.
Guo Y; Institute of Clinical Pharmacology, Zhengzhou University, Zhengzhou, 450052, Henan, China.
Zhou J; Institute of Clinical Pharmacology, Zhengzhou University, Zhengzhou, 450052, Henan, China.
Gu Y; Affiliated People's Hospital of Zhengzhou University, Zhengzhou, China.
Zhang C; Institute of Clinical Pharmacology, Zhengzhou University, Zhengzhou, 450052, Henan, China.
Gao N; Institute of Clinical Pharmacology, Zhengzhou University, Zhengzhou, 450052, Henan, China.
Wen Q; Institute of Clinical Pharmacology, Zhengzhou University, Zhengzhou, 450052, Henan, China.
Qiao H; Institute of Clinical Pharmacology, Zhengzhou University, Zhengzhou, 450052, Henan, China.

J Transl Med ; 19(1): 359, 2021 08 19.

Article em En | MEDLINE | ID: mdl-34412629

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; Proteína 6 Semelhante a Angiopoietina; Proteínas Semelhantes a Angiopoietina/genética; Biomarcadores; Biomarcadores Tumorais/genética; Carcinoma Hepatocelular/diagnóstico; Carcinoma Hepatocelular/genética; Citocromo P-450 CYP2D6/genética; Humanos; Neoplasias Hepáticas/diagnóstico; Neoplasias Hepáticas/genética; Prognóstico; Proteômica; Microambiente Tumoral

Palavras-chave

ANGPTL6; CYP2D6; Hepatocellular carcinoma; Polymorphisms; Proteomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: J Transl Med Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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