<i>In Vitro</i> Model for a Drug Assessment of Cytochrome P450 Family 3 Subfamily A Member 4 Substrates Using Human Induced Pluripotent Stem Cells and Genome Editing Technology.

Deguchi, Sayaka; Shintani, Tomohiro; Harada, Kazuo; Okamoto, Toru; Takemura, Akinori; Hirata, Kazumasa; Ito, Kousei; Takayama, Kazuo; Mizuguchi, Hiroyuki

In Vitro Model for a Drug Assessment of Cytochrome P450 Family 3 Subfamily A Member 4 Substrates Using Human Induced Pluripotent Stem Cells and Genome Editing Technology.

Deguchi, Sayaka; Shintani, Tomohiro; Harada, Kazuo; Okamoto, Toru; Takemura, Akinori; Hirata, Kazumasa; Ito, Kousei; Takayama, Kazuo; Mizuguchi, Hiroyuki.

Afiliação

Deguchi S; Laboratory of Biochemistry and Molecular BiologyGraduate School of Pharmaceutical SciencesOsaka UniversityOsakaJapan.
Shintani T; Laboratory of Biochemistry and Molecular BiologyGraduate School of Pharmaceutical SciencesOsaka UniversityOsakaJapan.
Harada K; Laboratory of Applied Environmental BiologyGraduate School of Pharmaceutical SciencesOsaka UniversityOsakaJapan.
Okamoto T; Institute for Advanced Co-creation Studies, Research Institute for Microbial DiseasesOsaka UniversityOsakaJapan.
Takemura A; Laboratory of BiopharmaceuticsGraduate School of Pharmaceutical SciencesChiba UniversityChibaJapan.
Hirata K; Laboratory of Applied Environmental BiologyGraduate School of Pharmaceutical SciencesOsaka UniversityOsakaJapan.
Ito K; Laboratory of BiopharmaceuticsGraduate School of Pharmaceutical SciencesChiba UniversityChibaJapan.
Takayama K; Laboratory of Biochemistry and Molecular BiologyGraduate School of Pharmaceutical SciencesOsaka UniversityOsakaJapan.
Mizuguchi H; Center for Induced Pluripotent Stem Cell Research and ApplicationKyoto UniversityKyotoJapan.

Hepatol Commun ; 5(8): 1385-1399, 2021 Aug.

Article em En | MEDLINE | ID: mdl-34430783

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Hepatol Commun Ano de publicação: 2021 Tipo de documento: Article

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