Restoring the Molecular Clockwork within the Suprachiasmatic Hypothalamus of an Otherwise Clockless Mouse Enables Circadian Phasing and Stabilization of Sleep-Wake Cycles and Reverses Memory Deficits.

Maywood, Elizabeth S; Chesham, Johanna E; Winsky-Sommerer, Raphaelle; Hastings, Michael H

Maywood, Elizabeth S; Chesham, Johanna E; Winsky-Sommerer, Raphaelle; Hastings, Michael H.

Afiliação

Maywood ES; Division of Neurobiology, Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom emaywood@mrc-lmb.cam.ac.uk mha@mrc-lmb.cam.ac.uk.
Chesham JE; Division of Neurobiology, Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom.
Winsky-Sommerer R; Surrey Sleep Research Centre, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XP, United Kingdom.
Hastings MH; Division of Neurobiology, Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom emaywood@mrc-lmb.cam.ac.uk mha@mrc-lmb.cam.ac.uk.

J Neurosci ; 41(41): 8562-8576, 2021 10 13.

Article em En | MEDLINE | ID: mdl-34446572

Assuntos

Ritmo Circadiano/fisiologia; Criptocromos/biossíntese; Sono/fisiologia; Núcleo Supraquiasmático/metabolismo; Vigília/fisiologia; Animais; Relógios Circadianos/fisiologia; Criptocromos/genética; Eletroencefalografia/métodos; Eletromiografia/métodos; Masculino; Transtornos da Memória; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout

Palavras-chave

NREM sleep; circadian; clock; cryptochrome; hippocampus; sleep homeostasis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sono / Núcleo Supraquiasmático / Vigília / Ritmo Circadiano / Criptocromos Limite: Animals Idioma: En Revista: J Neurosci Ano de publicação: 2021 Tipo de documento: Article

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