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Synthesis of novel calcium channel blockers with ACE2 inhibition and dual antihypertensive/anti-inflammatory effects: A possible therapeutic tool for COVID-19.
Mahgoub, Shahenda; Kotb El-Sayed, Mohamed-I; El-Shehry, Mohamed F; Mohamed Awad, Samir; Mansour, Yara E; Fatahala, Samar S.
Afiliação
  • Mahgoub S; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, P.O. Box, 11795 Cairo, Egypt. Electronic address: Shahenda.Mahgoub@pharm.helwan.edu.eg.
  • Kotb El-Sayed MI; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, P.O. Box, 11795 Cairo, Egypt; Department of Biochemistry, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt.
  • El-Shehry MF; Pesticide Chemistry Department, National Research Centre, P.O. Box, 12622 Dokki, Egypt.
  • Mohamed Awad S; Pharmaceutical Organic Chemistry Department, Helwan University, P.O. Box, 11795 Cairo, Egypt.
  • Mansour YE; Pharmaceutical Organic Chemistry Department, Helwan University, P.O. Box, 11795 Cairo, Egypt.
  • Fatahala SS; Pharmaceutical Organic Chemistry Department, Helwan University, P.O. Box, 11795 Cairo, Egypt. Electronic address: Samar_Saleh@pharm.helwan.edu.eg.
Bioorg Chem ; 116: 105272, 2021 11.
Article em En | MEDLINE | ID: mdl-34474305
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Inibidores da Enzima Conversora de Angiotensina / Bloqueadores dos Canais de Cálcio / Anti-Inflamatórios não Esteroides / Tratamento Farmacológico da COVID-19 / Anti-Hipertensivos Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Inibidores da Enzima Conversora de Angiotensina / Bloqueadores dos Canais de Cálcio / Anti-Inflamatórios não Esteroides / Tratamento Farmacológico da COVID-19 / Anti-Hipertensivos Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article