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Coupled Antigen and BLIMP1 Asymmetric Division With a Large Segregation Between Daughter Cells Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells and a DZ-to-LZ Ratio in the Germinal Center.
Merino Tejero, Elena; Lashgari, Danial; García-Valiente, Rodrigo; He, Jiaojiao; Robert, Philippe A; Meyer-Hermann, Michael; Guikema, Jeroen E J; Hoefsloot, Huub; van Kampen, Antoine H C.
Afiliação
  • Merino Tejero E; Bioinformatics Laboratory, Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands.
  • Lashgari D; Bioinformatics Laboratory, Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands.
  • García-Valiente R; Bioinformatics Laboratory, Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands.
  • He J; Bioinformatics and Systems Biology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Robert PA; Bioinformatics and Systems Biology, Institute for Life Sciences, University of Amsterdam, Amsterdam, Netherlands.
  • Meyer-Hermann M; Department for Systems Immunology and Braunschweig Integrated Centre of Systems Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
  • Guikema JEJ; Department for Systems Immunology and Braunschweig Integrated Centre of Systems Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
  • Hoefsloot H; Institute for Biochemistry, Biotechnology and Bioinformatics, Technische Universität Braunschweig, Braunschweig, Germany.
  • van Kampen AHC; Department of Pathology, Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam University Medical Centers, Amsterdam, Netherlands.
Front Immunol ; 12: 716240, 2021.
Article em En | MEDLINE | ID: mdl-34484219
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmócitos / Centro Germinativo / Divisão Celular Assimétrica / Fator 1 de Ligação ao Domínio I Regulador Positivo / Células B de Memória / Antígenos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Front Immunol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmócitos / Centro Germinativo / Divisão Celular Assimétrica / Fator 1 de Ligação ao Domínio I Regulador Positivo / Células B de Memória / Antígenos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Front Immunol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda