Licochalcone A inhibits MAS-related GPR family member X2-induced pseudo-allergic reaction by suppressing nuclear migration of nuclear factor-&#954;B.

Xue, Zhuoyin; Zhang, Yongjing; Zeng, Yingnan; Hu, Shiling; Bai, Haoyun; Wang, Jue; Jing, Huiling; Wang, Nan

Licochalcone A inhibits MAS-related GPR family member X2-induced pseudo-allergic reaction by suppressing nuclear migration of nuclear factor-κB.

Xue, Zhuoyin; Zhang, Yongjing; Zeng, Yingnan; Hu, Shiling; Bai, Haoyun; Wang, Jue; Jing, Huiling; Wang, Nan.

Afiliação

Xue Z; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Zhang Y; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Zeng Y; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Hu S; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Bai H; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Wang J; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Jing H; Xi'an Hospital of Traditional Chinese Medicine, Xi'an, China.
Wang N; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.

Phytother Res ; 35(11): 6270-6280, 2021 Nov.

Article em En | MEDLINE | ID: mdl-34486187

Assuntos

Chalconas; Hipersensibilidade; Degranulação Celular; Chalconas/farmacologia; Humanos; Hipersensibilidade/tratamento farmacológico; Mastócitos; NF-kappa B; Proteínas do Tecido Nervoso; Receptores Acoplados a Proteínas G/genética; Receptores de Neuropeptídeos

Palavras-chave

Licochalcone A; MRGPRX2; NF-κB; mast cells; pseudo-allergy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Chalconas / Hipersensibilidade Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Phytother Res Assunto da revista: TERAPIAS COMPLEMENTARES Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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