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Cancer-associated mutations in the p85α N-terminal SH2 domain activate a spectrum of receptor tyrosine kinases.
Li, Xinran; Lau, Amy Y T; Ng, Angel S N; Aldehaiman, Abdullah; Zhou, Yuan; Ng, Patrick K S; Arold, Stefan T; Cheung, Lydia W T.
Afiliação
  • Li X; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
  • Lau AYT; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
  • Ng ASN; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
  • Aldehaiman A; Biological and Environmental Science and Engineering, Computational Bioscience Research Center, King Abdullah University of Science and Technology, Thuwal 23955-6900, Saudi Arabia.
  • Zhou Y; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
  • Ng PKS; Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Arold ST; Biological and Environmental Science and Engineering, Computational Bioscience Research Center, King Abdullah University of Science and Technology, Thuwal 23955-6900, Saudi Arabia; stefan.arold@kaust.edu.sa lydiacwt@hku.hk.
  • Cheung LWT; Centre de Biologie Structurale, INSERM, Université de Montpellier, Montpellier 34090, France.
Proc Natl Acad Sci U S A ; 118(37)2021 09 14.
Article em En | MEDLINE | ID: mdl-34507989
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Classe I de Fosfatidilinositol 3-Quinases / Classe Ia de Fosfatidilinositol 3-Quinase Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Hong Kong
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Classe I de Fosfatidilinositol 3-Quinases / Classe Ia de Fosfatidilinositol 3-Quinase Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Hong Kong