R-Ras subfamily proteins elicit distinct physiologic effects and phosphoproteome alterations in neurofibromin-null MPNST cells.

Weber, Shannon M; Brossier, Nicole M; Prechtl, Amanda; Barnes, Stephen; Wilson, Landon S; Brosius, Stephanie N; Longo, Jody Fromm; Carroll, Steven L

Weber, Shannon M; Brossier, Nicole M; Prechtl, Amanda; Barnes, Stephen; Wilson, Landon S; Brosius, Stephanie N; Longo, Jody Fromm; Carroll, Steven L.

Afiliação

Weber SM; Department of Pathology and Laboratory Medicine (SMW, AP, JFL, SLC), MUSC Medical Scientist Training Program (SMW), Medical University of South Carolina, 171 Ashley Avenue, MSC 908, Charleston, SC, 29425-9080, USA.
Brossier NM; Departments of Pathology (NMB, SNB, SLC), Pharmacology and Toxicology (SB, LSW), UAB Medical Scientist Training Program (NMB, SNB), Birmingham, USA.
Prechtl A; The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Barnes S; Department of Pathology and Laboratory Medicine (SMW, AP, JFL, SLC), MUSC Medical Scientist Training Program (SMW), Medical University of South Carolina, 171 Ashley Avenue, MSC 908, Charleston, SC, 29425-9080, USA.
Wilson LS; Departments of Pathology (NMB, SNB, SLC), Pharmacology and Toxicology (SB, LSW), UAB Medical Scientist Training Program (NMB, SNB), Birmingham, USA.
Brosius SN; The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Longo JF; Department of Pediatrics, St. Louis Children's Hospital, St. Louis, USA.
Carroll SL; Department of Pathology and Laboratory Medicine (SMW, AP, JFL, SLC), MUSC Medical Scientist Training Program (SMW), Medical University of South Carolina, 171 Ashley Avenue, MSC 908, Charleston, SC, 29425-9080, USA.

Cell Commun Signal ; 19(1): 95, 2021 09 16.

Article em En | MEDLINE | ID: mdl-34530870

Assuntos

Proteínas de Membrana/genética; Proteínas Monoméricas de Ligação ao GTP/genética; Neurofibromatose 1/genética; Neurofibromina 1/genética; Neurofibrossarcoma/genética; Proteínas ras/genética; Quinases Associadas a rho/genética; Linhagem Celular Tumoral; Movimento Celular/genética; Proliferação de Células/genética; Regulação Neoplásica da Expressão Gênica/genética; Humanos; Neurofibromatose 1/patologia; Neurofibrossarcoma/patologia; Fosfoproteínas/genética; Fosforilação/genética; Proteoma/genética; Transdução de Sinais/genética

Palavras-chave

Malignant peripheral nerve sheath tumor; Neurofibromatosis; R-Ras; Ras; TC21

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neurofibromatose 1 / Neurofibrossarcoma / Proteínas ras / Proteínas Monoméricas de Ligação ao GTP / Neurofibromina 1 / Quinases Associadas a rho / Proteínas de Membrana Limite: Humans Idioma: En Revista: Cell Commun Signal Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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