Molecular epidemiology of hypervirulent Klebsiella pneumoniae: a systematic review and meta-analysis.
Iran J Microbiol
; 13(3): 257-265, 2021 Jun.
Article
em En
| MEDLINE
| ID: mdl-34540163
ABSTRACT
Classical (CKp) and hypervirulent (hvKp) Klebsiella pneumoniae are two different circulating pathotypes. The aim of this study was to assess the prevalence, epidemiology and molecular relatedness of hvKps using a systemic review and meta-analysis. The data extracted from Medline, Embase, and Web of Science and finally 14 studies met the eligible criteria. To combine prevalence proportions of all studies, we performed the metaprop command embedded in the Meta package software. Totally, of 1814 K. pneumoniae isolates, 21.7% (394/1814) were hvKp. The molecular typing showed that all hvKp isolates were grouped into 50 different sequence types (STs) of them ST23, ST11, ST65 and ST86 were common. K1, K2 and K64 were dominant capsule serotypes that strongly related to ST23, ST65 and ST11, respectively. It seems that clonal group 23 (CG23) is associated with liver abscess and CG11 related to various clinical sources.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Risk_factors_studies
/
Screening_studies
/
Systematic_reviews
Idioma:
En
Revista:
Iran J Microbiol
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Irã