Neurological Manifestations Associated with Parvovirus B19 Infection in Immunocompetent Children: Case Series and Systematic Review.
J Trop Pediatr
; 67(4)2021 08 27.
Article
em En
| MEDLINE
| ID: mdl-34545404
ABSTRACT
An increasing number of reports have described human parvovirus B19 infection in association with a variety of neurological manifestations, especially in children. This study assessed the clinical and laboratory outcomes found in a case series of immunocompetent children who tested positive for parvovirus B19 by qualitative polymerase chain reaction assays of cerebrospinal fluid, in a tertiary referral center in the western Brazilian Amazon. We screened 178 children with clinically diagnosed central nervous system infections (meningoencephalitis). Of these, five (2.8%) were positive for parvovirus B19. A literature review also presented herein identified a further 50 cases of parvovirus B19 with neurological manifestations. Thus, even if the classic signs of parvovirus B19 infection are absent, such as the well-known rash, children with signs of neurological infection should also be evaluated for parvovirus B19 infection.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Parvovirus B19 Humano
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Eritema Infeccioso
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Infecções por Parvoviridae
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Doenças do Sistema Nervoso
Tipo de estudo:
Diagnostic_studies
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Prognostic_studies
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Qualitative_research
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Risk_factors_studies
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Systematic_reviews
Limite:
Child
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Humans
Idioma:
En
Revista:
J Trop Pediatr
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Brasil