Autoinflammatory syndromes in neurology: when our first line of defence misbehaves.
Pract Neurol
; 22(2): 145-153, 2022 Apr.
Article
em En
| MEDLINE
| ID: mdl-34599092
ABSTRACT
Autoinflammatory syndromes result from a defective innate immune system. They are characterised by unexplained fever and systemic inflammation involving the skin, muscle, joints, serosa and eyes, along with elevated acute phase reactants. Autoinflammatory syndromes are increasingly recognised as a cause of neurological disease with a diverse range of manifestations. Corticosteroids, colchicine and targeted therapies are effective if started early, and hence the importance of recognising these syndromes. Here, we review the neurological features of specific autoinflammatory syndromes and our approach (as adult neurologists) to their diagnosis.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Hereditárias Autoinflamatórias
/
Doenças do Sistema Nervoso
/
Neurologia
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Pract Neurol
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Nova Zelândia