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Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms.
Hu, Haichuan; Piotrowska, Zofia; Hare, Patricia J; Chen, Huidong; Mulvey, Hillary E; Mayfield, Aislinn; Noeen, Sundus; Kattermann, Krystina; Greenberg, Max; Williams, August; Riley, Amanda K; Wilson, Jarad J; Mao, Ying-Qing; Huang, Ruo-Pan; Banwait, Mandeep K; Ho, Jeffrey; Crowther, Giovanna S; Hariri, Lida P; Heist, Rebecca S; Kodack, David P; Pinello, Luca; Shaw, Alice T; Mino-Kenudson, Mari; Hata, Aaron N; Sequist, Lecia V; Benes, Cyril H; Niederst, Matthew J; Engelman, Jeffrey A.
Afiliação
  • Hu H; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA. Electronic address: hhu5@mgh.harvard.edu.
  • Piotrowska Z; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Hare PJ; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Chen H; Massachusetts General Hospital and Department of Pathology, Harvard Medical School, Boston, MA 02114, USA; Molecular Pathology Unit, Massachusetts General Hospital Research Institute, Charlestown, MA 02129, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
  • Mulvey HE; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Mayfield A; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Noeen S; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Kattermann K; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Greenberg M; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Williams A; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Riley AK; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Wilson JJ; RayBiotech Inc, Norcross, GA 30092, USA.
  • Mao YQ; RayBiotech Inc, Norcross, GA 30092, USA; RayBiotech Inc, Guangzhou, Guangdong 510630, China.
  • Huang RP; RayBiotech Inc, Norcross, GA 30092, USA; RayBiotech Inc, Guangzhou, Guangdong 510630, China; Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, Guangdong 510095, China.
  • Banwait MK; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Ho J; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Crowther GS; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Hariri LP; Massachusetts General Hospital and Department of Pathology, Harvard Medical School, Boston, MA 02114, USA.
  • Heist RS; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Kodack DP; Novartis Institutes for BioMedical Research, Cambridge, MA 02139, USA.
  • Pinello L; Massachusetts General Hospital and Department of Pathology, Harvard Medical School, Boston, MA 02114, USA; Molecular Pathology Unit, Massachusetts General Hospital Research Institute, Charlestown, MA 02129, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
  • Shaw AT; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Mino-Kenudson M; Massachusetts General Hospital and Department of Pathology, Harvard Medical School, Boston, MA 02114, USA.
  • Hata AN; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Sequist LV; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA.
  • Benes CH; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, MA 02114, USA. Electronic address: cyrilbenes@gmail.com.
  • Niederst MJ; Novartis Institutes for BioMedical Research, Cambridge, MA 02139, USA. Electronic address: matt.niederst@novartis.com.
  • Engelman JA; Novartis Institutes for BioMedical Research, Cambridge, MA 02139, USA. Electronic address: jengelman1@gmail.com.
Cancer Cell ; 39(11): 1531-1547.e10, 2021 11 08.
Article em En | MEDLINE | ID: mdl-34624218
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento de Hepatócito / Carcinoma Pulmonar de Células não Pequenas / Fator 7 de Crescimento de Fibroblastos / Fibroblastos Associados a Câncer / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento de Hepatócito / Carcinoma Pulmonar de Células não Pequenas / Fator 7 de Crescimento de Fibroblastos / Fibroblastos Associados a Câncer / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article