Potentiation of long-acting ß<sub>2</sub>-agonist and glucocorticoid responses in human airway epithelial cells by modulation of intracellular cAMP.

Kim, Yechan; Hou, Vincent; Huff, Ryan D; Aguiar, Jennifer A; Revill, Spencer; Tiessen, Nicholas; Cao, Quynh; Miller, Matthew S; Inman, Mark D; Ask, Kjetil; Doxey, Andrew C; Hirota, Jeremy A

Potentiation of long-acting ß₂-agonist and glucocorticoid responses in human airway epithelial cells by modulation of intracellular cAMP.

Kim, Yechan; Hou, Vincent; Huff, Ryan D; Aguiar, Jennifer A; Revill, Spencer; Tiessen, Nicholas; Cao, Quynh; Miller, Matthew S; Inman, Mark D; Ask, Kjetil; Doxey, Andrew C; Hirota, Jeremy A.

Afiliação

Kim Y; Firestone Institute for Respiratory Health-Division of Respirology, Department of Medicine, McMaster University, Hamilton, ON, L8N 4A6, Canada.
Hou V; Firestone Institute for Respiratory Health-Division of Respirology, Department of Medicine, McMaster University, Hamilton, ON, L8N 4A6, Canada.
Huff RD; Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, V6H 3Z, Canada.
Aguiar JA; Department of Biology, University of Waterloo, Waterloo, ON, N2L 3G1, Canada.
Revill S; Firestone Institute for Respiratory Health-Division of Respirology, Department of Medicine, McMaster University, Hamilton, ON, L8N 4A6, Canada.
Tiessen N; Firestone Institute for Respiratory Health-Division of Respirology, Department of Medicine, McMaster University, Hamilton, ON, L8N 4A6, Canada.
Cao Q; Firestone Institute for Respiratory Health-Division of Respirology, Department of Medicine, McMaster University, Hamilton, ON, L8N 4A6, Canada.
Miller MS; Department of Biochemistry, McMaster University, Hamilton, ON, L8S 4K1, Canada.
Inman MD; McMaster Immunology Research Centre, McMaster University, Hamilton, ON, L8S 4K1, Canada.
Ask K; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON, L8S 4K1, Canada.
Doxey AC; Firestone Institute for Respiratory Health-Division of Respirology, Department of Medicine, McMaster University, Hamilton, ON, L8N 4A6, Canada.
Hirota JA; Firestone Institute for Respiratory Health-Division of Respirology, Department of Medicine, McMaster University, Hamilton, ON, L8N 4A6, Canada.

Respir Res ; 22(1): 266, 2021 Oct 19.

Article em En | MEDLINE | ID: mdl-34666750

Assuntos

Agonistas de Receptores Adrenérgicos beta 2/farmacologia; Budesonida/farmacologia; AMP Cíclico/metabolismo; Células Epiteliais/efeitos dos fármacos; Fumarato de Formoterol/farmacologia; Glucocorticoides/farmacologia; Pulmão/efeitos dos fármacos; Aminopiridinas/farmacologia; Benzamidas/farmacologia; Benzotiazóis/farmacologia; Linhagem Celular; Quimiocinas/metabolismo; Nucleotídeo Cíclico Fosfodiesterase do Tipo 4/metabolismo; Ácidos Cicloexanocarboxílicos/farmacologia; Ciclopropanos/farmacologia; Sinergismo Farmacológico; Quimioterapia Combinada; Células Epiteliais/metabolismo; Humanos; Pulmão/metabolismo; Proteínas Associadas à Resistência a Múltiplos Medicamentos/antagonistas & inibidores; Proteínas Associadas à Resistência a Múltiplos Medicamentos/metabolismo; Nitrilas/farmacologia; Inibidores da Fosfodiesterase 4/farmacologia; Rolipram/farmacologia; Sistemas do Segundo Mensageiro; Triazóis/farmacologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: AMP Cíclico / Budesonida / Células Epiteliais / Agonistas de Receptores Adrenérgicos beta 2 / Fumarato de Formoterol / Glucocorticoides / Pulmão Limite: Humans Idioma: En Revista: Respir Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá

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