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Either IL-7 activation of JAK-STAT or BEZ inhibition of PI3K-AKT-mTOR pathways dominates the single-cell phosphosignature of ex vivo treated pediatric T-cell acute lymphoblastic leukemia cells.
Kuzilková, Daniela; Bugarin, Cristina; Rejlova, Katerina; Schulz, Axel R; Mei, Henrik E; Paganin, Maddalena; Biffi, Alessandra; Biondi, Andrea; Kalina, Tomas; Gaipa, Giuseppe.
Afiliação
  • Kuzilková D; Childhood Leukaemia Investigation Prague, Czech Republic; Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague, Czech Republic.
  • Bugarin C; Fondazione Tettamanti, Clinica Pediatrica Università degli Studi Milano Bicocca, Monza (MB), Italy.
  • Rejlova K; Childhood Leukaemia Investigation Prague, Czech Republic; Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague, Czech Republic.
  • Schulz AR; German Rheumatism Research Center Berlin (DRFZ), a Leibniz Institute, Berlin, Germany.
  • Mei HE; German Rheumatism Research Center Berlin (DRFZ), a Leibniz Institute, Berlin, Germany.
  • Paganin M; Pediatric Hematology, Oncology and Stem Cell Transplant Division, Women and Child Health Department, University of Padova, Padova, Italy.
  • Biffi A; Pediatric Hematology, Oncology and Stem Cell Transplant Division, Women and Child Health Department, University of Padova, Padova, Italy.
  • Biondi A; Fondazione Tettamanti, Clinica Pediatrica Università degli Studi Milano Bicocca, Monza (MB), Italy. andrea.biondi@unimib.it.
  • Kalina T; Childhood Leukaemia Investigation Prague, Czech Republic; Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague, Czech Republic.
  • Gaipa G; Fondazione Tettamanti, Clinica Pediatrica Università degli Studi Milano Bicocca, Monza (MB), Italy.
Haematologica ; 107(6): 1293-1310, 2022 06 01.
Article em En | MEDLINE | ID: mdl-34670357
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-7 / Leucemia-Linfoma Linfoblástico de Células T Precursoras Limite: Child / Humans Idioma: En Revista: Haematologica Ano de publicação: 2022 Tipo de documento: Article País de afiliação: República Tcheca
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-7 / Leucemia-Linfoma Linfoblástico de Células T Precursoras Limite: Child / Humans Idioma: En Revista: Haematologica Ano de publicação: 2022 Tipo de documento: Article País de afiliação: República Tcheca