Targeted Isolation of a Cytotoxic Cyclic Hexadepsipeptide from the Mesophotic Zone Sponge-Associated Fungus <i>Cymostachys</i> sp. NBUF082.

Yuan, Ye; Li, Te; Wang, Tingting; Naman, C Benjamin; Ye, Jing; Wu, Xingxin; Lazaro, J Enrico H; Yan, Xiaojun; He, Shan

Targeted Isolation of a Cytotoxic Cyclic Hexadepsipeptide from the Mesophotic Zone Sponge-Associated Fungus Cymostachys sp. NBUF082.

Yuan, Ye; Li, Te; Wang, Tingting; Naman, C Benjamin; Ye, Jing; Wu, Xingxin; Lazaro, J Enrico H; Yan, Xiaojun; He, Shan.

Afiliação

Yuan Y; Department of Marine Pharmacy, Li Dak Sum Marine Biopharmaceutical Research Center, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315832, China.
Li T; School of Marine Science, Ningbo University, Ningbo 315832, China.
Wang T; Department of Marine Pharmacy, Li Dak Sum Marine Biopharmaceutical Research Center, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315832, China.
Naman CB; School of Marine Science, Ningbo University, Ningbo 315832, China.
Ye J; Department of Marine Pharmacy, Li Dak Sum Marine Biopharmaceutical Research Center, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315832, China.
Wu X; Department of Marine Pharmacy, Li Dak Sum Marine Biopharmaceutical Research Center, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315832, China.
Lazaro JEH; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Yan X; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
He S; National Institute of Molecular Biology and Biotechnology, University of the Philippines Diliman, Quezon 1101, Philippines.

Mar Drugs ; 19(10)2021 Oct 11.

Article em En | MEDLINE | ID: mdl-34677465

Assuntos

Antineoplásicos/farmacologia; Hypocreales/química; Peptídeos Cíclicos/farmacologia; Poríferos/microbiologia; Animais; Antineoplásicos/química; Organismos Aquáticos; Linhagem Celular Tumoral/efeitos dos fármacos; Cromatografia Líquida; Ensaios de Seleção de Medicamentos Antitumorais; Humanos; Peptídeos Cíclicos/química; Espectrometria de Massas em Tandem

Palavras-chave

cytotoxicity; hexadepsipeptide; mesophotic zone; sponge-associated fungi; sponges

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Poríferos / Hypocreales / Antineoplásicos Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Mar Drugs Assunto da revista: BIOLOGIA / FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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