Platelet-Derived PCSK9 Is Associated with LDL Metabolism and Modulates Atherothrombotic Mechanisms in Coronary Artery Disease.

Petersen-Uribe, Álvaro; Kremser, Marcel; Rohlfing, Anne-Katrin; Castor, Tatsiana; Kolb, Kyra; Dicenta, Valerie; Emschermann, Frederic; Li, Bo; Borst, Oliver; Rath, Dominik; Müller, Karin Anne Lydia; Gawaz, Meinrad Paul

Petersen-Uribe, Álvaro; Kremser, Marcel; Rohlfing, Anne-Katrin; Castor, Tatsiana; Kolb, Kyra; Dicenta, Valerie; Emschermann, Frederic; Li, Bo; Borst, Oliver; Rath, Dominik; Müller, Karin Anne Lydia; Gawaz, Meinrad Paul.

Afiliação

Petersen-Uribe Á; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
Kremser M; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
Rohlfing AK; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
Castor T; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
Kolb K; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
Dicenta V; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
Emschermann F; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
Li B; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
Borst O; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
Rath D; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
Müller KAL; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
Gawaz MP; Department of Cardiology and Angiology, University Hospital Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.

Int J Mol Sci ; 22(20)2021 Oct 16.

Article em En | MEDLINE | ID: mdl-34681838

Assuntos

Aterosclerose/metabolismo; Plaquetas/fisiologia; Doença da Artéria Coronariana/metabolismo; Lipoproteínas LDL/metabolismo; Pró-Proteína Convertase 9/fisiologia; Idoso; Idoso de 80 Anos ou mais; Diferenciação Celular/efeitos dos fármacos; Movimento Celular/efeitos dos fármacos; Estudos de Coortes; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Ativação Plaquetária/efeitos dos fármacos; Agregação Plaquetária/efeitos dos fármacos; Contagem de Plaquetas/estatística & dados numéricos; Trombose/metabolismo

Palavras-chave

LDL; PCSK9; atherothrombosis; platelets; thrombo-inflammation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plaquetas / Doença da Artéria Coronariana / Aterosclerose / Pró-Proteína Convertase 9 / Lipoproteínas LDL Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha

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