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Tanshinone IIA derivatives induced S-phase arrest through stabilizing c-myc G-quadruplex DNA to regulate ROS-mediated PI3K/Akt/mTOR pathway.
Wang, Teng; Zou, Jun; Wu, Qiong; Wang, Rui; Yuan, Chan-Ling; Shu, Jing; Zhai, Bing-Bing; Huang, Xiao-Ting; Liu, Ning-Zhi; Hua, Feng-Yang; Wang, Xi-Cheng; Mei, Wen-Jie.
Afiliação
  • Wang T; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
  • Zou J; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
  • Wu Q; Guangdong Province Engineering Technology Centre for Molecular Probe and Bio-medicine Imaging, Guangzhou, 510006, China. Electronic address: wuqiongniu.1113@163.com.
  • Wang R; The First Affiliation Hospital, Guangdong Pharmaceutical University, Guangzhou, 510062, China.
  • Yuan CL; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
  • Shu J; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
  • Zhai BB; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
  • Huang XT; Guangdong Province Engineering Technology Centre for Molecular Probe and Bio-medicine Imaging, Guangzhou, 510006, China.
  • Liu NZ; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
  • Hua FY; The First Affiliation Hospital, Guangdong Pharmaceutical University, Guangzhou, 510062, China.
  • Wang XC; The First Affiliation Hospital, Guangdong Pharmaceutical University, Guangzhou, 510062, China; Guangdong Province Engineering Technology Centre for Molecular Probe and Bio-medicine Imaging, Guangzhou, 510006, China. Electronic address: 13902400598@126.com.
  • Mei WJ; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, China; Guangdong Province Engineering Technology Centre for Molecular Probe and Bio-medicine Imaging, Guangzhou, 510006, China. Electronic address: wenjiemei@126.com.
Eur J Pharmacol ; 912: 174586, 2021 Dec 05.
Article em En | MEDLINE | ID: mdl-34710368
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-myc / Fase S / Fosfatidilinositol 3-Quinases / Abietanos / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-myc / Fase S / Fosfatidilinositol 3-Quinases / Abietanos / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China