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Neutrophil Extracellular Trap Density Increases With Increasing Histopathological Severity of Crohn's Disease.
Schroder, Angie L; Chami, Belal; Liu, Yuyang; Doyle, Chloe M; El Kazzi, Mary; Ahlenstiel, Golo; Ahmad, Gulfam; Pathma-Nathan, Nimalan; Collins, Geoff; Toh, James; Harman, Andrew; Byrne, Scott; Ctercteko, Grahame; Witting, Paul K.
Afiliação
  • Schroder AL; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, NSW, Australia.
  • Chami B; Charles Perkins Centre, The University of Sydney, NSW, Australia.
  • Liu Y; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, NSW, Australia.
  • Doyle CM; Charles Perkins Centre, The University of Sydney, NSW, Australia.
  • El Kazzi M; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, NSW, Australia.
  • Ahlenstiel G; Charles Perkins Centre, The University of Sydney, NSW, Australia.
  • Ahmad G; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, NSW, Australia.
  • Pathma-Nathan N; Westmead Institute for Medical Research, Centre for Immunology and Allergy Research, Westmead, NSW, Australia.
  • Collins G; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, NSW, Australia.
  • Toh J; Charles Perkins Centre, The University of Sydney, NSW, Australia.
  • Harman A; Western Sydney University, Westmead Clinical School and The Westmead Institute for Medical Research, Blacktown Hospital, Blacktown, NSW, Australia.
  • Byrne S; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, NSW, Australia.
  • Ctercteko G; Charles Perkins Centre, The University of Sydney, NSW, Australia.
  • Witting PK; Westmead Institute for Medical Research, Centre for Immunology and Allergy Research, Westmead, NSW, Australia.
Inflamm Bowel Dis ; 28(4): 586-598, 2022 03 30.
Article em En | MEDLINE | ID: mdl-34724042
Our data show for the first time that the density of neutrophil extracellular trap formed in the bowel of Crohn's disease patients increases with increasing disease severity, suggesting that myeloperoxidase-mediated host-tissue damage may play a role in disease pathogenesis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Crohn / Armadilhas Extracelulares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Inflamm Bowel Dis Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Crohn / Armadilhas Extracelulares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Inflamm Bowel Dis Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália