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Pandemic Response Requires Research Samples: A U.S. Safety-Net Hospital's Experience and Call for National Action.
Ragan, Elizabeth J; McCallum, Caitryn; Marathe, Jai; Cole, Manisha; Hofman, Melissa; Henderson, Andrew J; Flack, Tyler; Miller, Nancy S; Burks, Eric J; Zhao, Grace Qing; Denis, Ridiane; Lin, Nina H; Jacobson, Karen R; Andry, Christopher D; Pelton, Stephen I; Duffy, Elizabeth R; Bhadelia, Nahid.
Afiliação
  • Ragan EJ; Section of Infectious Diseases and Research Operations, Boston Medical Center, Boston, Massachusetts (E.J.R.).
  • McCallum C; Section of Infectious Diseases, Boston Medical Center, and Center for Emerging Infectious Diseases Policy and Research, Boston University, Boston, Massachusetts (C.M.).
  • Marathe J; Section of Infectious Diseases, Boston Medical Center, Boston, Massachusetts (J.M., N.H.L., K.R.J.).
  • Cole M; Department of Pathology and Laboratory Medicine, Boston Medical Center, Boston, Massachusetts (M.C., N.S.M., E.J.B., G.Q.Z.).
  • Hofman M; Clinical Data Warehouse, Boston Medical Center, Boston, Massachusetts (M.H.).
  • Henderson AJ; Section of Infectious Diseases, Boston Medical Center, and Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts (A.J.H.).
  • Flack T; Research Operations, Boston Medical Center, Boston, Massachusetts (T.F.).
  • Miller NS; Department of Pathology and Laboratory Medicine, Boston Medical Center, Boston, Massachusetts (M.C., N.S.M., E.J.B., G.Q.Z.).
  • Burks EJ; Department of Pathology and Laboratory Medicine, Boston Medical Center, Boston, Massachusetts (M.C., N.S.M., E.J.B., G.Q.Z.).
  • Zhao GQ; Department of Pathology and Laboratory Medicine, Boston Medical Center, Boston, Massachusetts (M.C., N.S.M., E.J.B., G.Q.Z.).
  • Denis R; General Clinical Research Unit, Boston University, Boston, Massachusetts (R.D.).
  • Lin NH; Section of Infectious Diseases, Boston Medical Center, Boston, Massachusetts (J.M., N.H.L., K.R.J.).
  • Jacobson KR; Section of Infectious Diseases, Boston Medical Center, Boston, Massachusetts (J.M., N.H.L., K.R.J.).
  • Andry CD; Department of Pathology and Laboratory Medicine, Boston Medical Center, and Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts (C.D.A., E.R.D.).
  • Pelton SI; Section of Pediatric Infectious Diseases, Department of Pediatrics, Boston University Medical Center, Department of Epidemiology, Boston University School of Public Health, and Maxwell Finland Laboratory for Infectious Diseases, Boston, Massachusetts (S.I.P.).
  • Duffy ER; Department of Pathology and Laboratory Medicine, Boston Medical Center, and Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts (C.D.A., E.R.D.).
  • Bhadelia N; Section of Infectious Diseases, Boston Medical Center, and Center for Emerging Infectious Diseases Policy and Research and National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts (N.B.).
Ann Intern Med ; 174(12): 1727-1732, 2021 12.
Article em En | MEDLINE | ID: mdl-34724402
ABSTRACT
Biorepositories provide a critical resource for gaining knowledge of emerging infectious diseases and offer a mechanism to rapidly respond to outbreaks; the emergence of the novel coronavirus, SARS-CoV-2, has proved their importance. During the COVID-19 pandemic, the absence of centralized, national biorepository efforts meant that the onus fell on individual institutions to establish sample repositories. As a safety-net hospital, Boston Medical Center (BMC) recognized the importance of creating a COVID-19 biorepository to both support critical science at BMC and ensure representation in research for its urban patient population, most of whom are from underserved communities. This article offers a realistic overview of the authors' experience in establishing this biorepository at the onset of the COVID-19 pandemic during the height of the first surge of cases in Boston, Massachusetts, with the hope that the challenges and solutions described are useful to other institutions. Going forward, funders, policymakers, and infectious disease and public health communities must support biorepository implementation as an essential element of future pandemic preparedness.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Manejo de Espécimes / Controle de Infecções / Centros Médicos Acadêmicos / Pandemias / COVID-19 Limite: Humans País/Região como assunto: America do norte Idioma: En Revista: Ann Intern Med Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Manejo de Espécimes / Controle de Infecções / Centros Médicos Acadêmicos / Pandemias / COVID-19 Limite: Humans País/Região como assunto: America do norte Idioma: En Revista: Ann Intern Med Ano de publicação: 2021 Tipo de documento: Article