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mTOR inhibitor PP242 increases antitumor activity of sulforaphane by blocking Akt/mTOR pathway in esophageal squamous cell carcinoma.
Lu, Zhaoming; Zhang, Yalin; Xu, Yujia; Wei, Huiyun; Zhao, Wen; Wang, Pengju; Li, Yan; Hou, Guiqin.
Afiliação
  • Lu Z; State Key Laboratory of Esophageal Cancer Prevention & Treatment, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
  • Zhang Y; Collaborative Innovation Center of Cancer Chemoprevention, Zhengzhou, 450001, Henan Province, China.
  • Xu Y; State Key Laboratory of Esophageal Cancer Prevention & Treatment, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
  • Wei H; State Key Laboratory of Esophageal Cancer Prevention & Treatment, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
  • Zhao W; State Key Laboratory of Esophageal Cancer Prevention & Treatment, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
  • Wang P; State Key Laboratory of Esophageal Cancer Prevention & Treatment, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
  • Li Y; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou University, Zhengzhou, 450052, China.
  • Hou G; Sino-British Research Centre for Molecular Oncology, School of Basic Medical Sciences, National Centre for International Research in Cell and Gene Therapy, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, 450052, China.
Mol Biol Rep ; 49(1): 451-461, 2022 Jan.
Article em En | MEDLINE | ID: mdl-34731371

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Purinas / Sulfóxidos / Transdução de Sinais / Isotiocianatos / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Inibidores de MTOR / Indóis Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Biol Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Purinas / Sulfóxidos / Transdução de Sinais / Isotiocianatos / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Inibidores de MTOR / Indóis Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Biol Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China