The Effect of Sera from Children with Obstructive Sleep Apnea Syndrome (OSAS) on Human Cardiomyocytes Differentiated from Human Embryonic Stem Cells.

Haddad, Hen; Etzion, Sharon; Rabinski, Tatiana; Ofir, Rivka; Regev, Danielle; Etzion, Yoram; Gopas, Jacob; Goldbart, Aviv

Haddad, Hen; Etzion, Sharon; Rabinski, Tatiana; Ofir, Rivka; Regev, Danielle; Etzion, Yoram; Gopas, Jacob; Goldbart, Aviv.

Afiliação

Haddad H; Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Etzion S; Regenerative Medicine & Stem Cell Research Center, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Rabinski T; Regenerative Medicine & Stem Cell Research Center, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Ofir R; Regenerative Medicine & Stem Cell Research Center, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Regev D; Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Etzion Y; Regenerative Medicine & Stem Cell Research Center, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Gopas J; Cardiac Arrhythmia Research Laboratory, Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Goldbart A; Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva 8410501, Israel.

Int J Mol Sci ; 22(21)2021 Oct 22.

Article em En | MEDLINE | ID: mdl-34768848

Assuntos

Doenças Cardiovasculares/patologia; Frequência Cardíaca/efeitos dos fármacos; Contração Miocárdica/efeitos dos fármacos; Miócitos Cardíacos/metabolismo; Apneia Obstrutiva do Sono/sangue; Sinalização do Cálcio/efeitos dos fármacos; Células Cultivadas; Criança; Células-Tronco Embrionárias Humanas/citologia; Humanos; Miócitos Cardíacos/citologia; Miócitos Cardíacos/efeitos dos fármacos; Subunidade p50 de NF-kappa B/metabolismo; Soro; Apneia Obstrutiva do Sono/patologia; Fator de Transcrição RelA/metabolismo

Palavras-chave

NF-κB; beating rate; cardiomyocytes (CM) derived from human embryonic stem cells (hES); contractility; inflammation; intracellular [Ca2+]i signaling; obstructive sleep apnea; sera

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Cardiovasculares / Apneia Obstrutiva do Sono / Miócitos Cardíacos / Frequência Cardíaca / Contração Miocárdica Tipo de estudo: Prognostic_studies Limite: Child / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Israel

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