Control of cell signaling by Arf GTPases and their regulators: Focus on links to cancer and other GTPase families.
Biochim Biophys Acta Mol Cell Res
; 1869(2): 119171, 2022 02.
Article
em En
| MEDLINE
| ID: mdl-34774605
ABSTRACT
The ADP-ribosylation factors (Arfs) comprise a family of regulatory GTP binding proteins. The Arfs regulate membrane trafficking and cytoskeleton remodeling, processes critical for eukaryotes and which have been the focus of most studies on Arfs. A more limited literature describes a role in signaling and in integrating several signaling pathways to bring about specific cell behaviors. Here, we will highlight work describing function of Arf1, Arf6 and several effectors and regulators of Arfs in signaling.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Regulação Neoplásica da Expressão Gênica
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Fator 1 de Ribosilação do ADP
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Fator 6 de Ribosilação do ADP
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GTP Fosfo-Hidrolases
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Neoplasias
Limite:
Animals
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Humans
Idioma:
En
Revista:
Biochim Biophys Acta Mol Cell Res
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos