Astaxanthin attenuated hyperuricemia and kidney inflammation by inhibiting uric acid synthesis and the NF-&#954; B/NLRP3 signaling pathways in potassium oxonate and hypoxanthine-induced hyperuricemia mice.

Zhuang, Jiangchao; Zhou, Xie; Liu, Ting; Zhang, Shuai; Yuan, Falei; Zhang, Leifang; Yang, Zuisu; Chen, Yan

Astaxanthin attenuated hyperuricemia and kidney inflammation by inhibiting uric acid synthesis and the NF-κ B/NLRP3 signaling pathways in potassium oxonate and hypoxanthine-induced hyperuricemia mice.

Zhuang, Jiangchao; Zhou, Xie; Liu, Ting; Zhang, Shuai; Yuan, Falei; Zhang, Leifang; Yang, Zuisu; Chen, Yan.

Afiliação

Zhuang J; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University.
Zhou X; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University.
Liu T; Zhoushan Institute for Food and Drug Control, Zhoushan, China.
Zhang S; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University.
Yuan F; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University.
Zhang L; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University.
Yang Z; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University.
Chen Y; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University;, Email: cyancy@zjou.edu.cn.

Pharmazie ; 76(11): 551-558, 2021 11 01.

Article em En | MEDLINE | ID: mdl-34782040

Assuntos

Hiperuricemia; Animais; Antioxidantes/farmacologia; Hiperuricemia/induzido quimicamente; Hiperuricemia/tratamento farmacológico; Hiperuricemia/metabolismo; Hipoxantina/efeitos adversos; Inflamação/tratamento farmacológico; Inflamação/patologia; Rim/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos ICR; NF-kappa B/metabolismo; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo; Ácido Oxônico; Transdução de Sinais; Fator de Transcrição RelA/metabolismo; Ácido Úrico/metabolismo; Ácido Úrico/farmacologia; Xantina Oxidase/efeitos adversos; Xantina Oxidase/metabolismo; Xantofilas

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hiperuricemia Limite: Animals Idioma: En Revista: Pharmazie Assunto da revista: FARMACIA Ano de publicação: 2021 Tipo de documento: Article

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