Drug Delivery across Barriers to the Middle and Inner Ear.
Adv Funct Mater
; 31(44)2021 Oct 26.
Article
em En
| MEDLINE
| ID: mdl-34795553
ABSTRACT
The prevalence of ear disorders has spurred efforts to develop drug delivery systems to treat these conditions. Here, recent advances in drug delivery systems that access the ear through the tympanic membrane (TM) are reviewed. Such methods are either non-invasive (placed on the surface of the TM), or invasive (placed in the middle ear, ideally on the round window [RW]). The major hurdles to otic drug delivery are identified and highlighted the representative examples of drug delivery systems used for drug delivery across the TM to the middle and (crossing the RW also) inner ear.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Revista:
Adv Funct Mater
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Estados Unidos