Deciphering cell signaling networks with massively multiplexed biosensor barcoding.

Yang, Jr-Ming; Chi, Wei-Yu; Liang, Jessica; Takayanagi, Saki; Iglesias, Pablo A; Huang, Chuan-Hsiang

Yang, Jr-Ming; Chi, Wei-Yu; Liang, Jessica; Takayanagi, Saki; Iglesias, Pablo A; Huang, Chuan-Hsiang.

Afiliação

Yang JM; Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA. Electronic address: jyang38@jhmi.edu.
Chi WY; Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA.
Liang J; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA.
Takayanagi S; XDBio Graduate Program, Johns Hopkins School of Medicine, MD 21205, USA.
Iglesias PA; Department of Electrical and Computer Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Huang CH; Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA. Electronic address: chuang29@jhmi.edu.

Cell ; 184(25): 6193-6206.e14, 2021 12 09.

Article em En | MEDLINE | ID: mdl-34838160

Assuntos

Técnicas Biossensoriais/métodos; Células/ultraestrutura; Microscopia de Fluorescência/métodos; Análise de Célula Única/métodos; Linhagem Celular Tumoral; Humanos

Palavras-chave

KRAS; adaptation; barcode; cell non-autonomous effect; fluorescent biosensor; live cell imaging; machine learning; multiplexing; receptor tyrosine kinase; signaling network

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Células / Análise de Célula Única / Microscopia de Fluorescência Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2021 Tipo de documento: Article

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