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Pharmacokinetics, Mass Balance, and Metabolism of the Novel Urate Transporter 1 Inhibitor [14C]HR011303 in Humans: Metabolism Is Mediated Predominantly by UDP-Glucuronosyltransferase.
Zheng, Yuandong; Zhang, Hua; Liu, Mengling; Li, Guangze; Ma, Sheng; Zhang, Zhe; Lin, Hongda; Zhan, Yan; Chen, Zhendong; Zhong, Dafang; Miao, Liyan; Diao, Xingxing.
Afiliação
  • Zheng Y; Shanghai Center for Drug Metabolism and Pharmacokinetics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); Department of Cli
  • Zhang H; Shanghai Center for Drug Metabolism and Pharmacokinetics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); Department of Cli
  • Liu M; Shanghai Center for Drug Metabolism and Pharmacokinetics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); Department of Cli
  • Li G; Shanghai Center for Drug Metabolism and Pharmacokinetics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); Department of Cli
  • Ma S; Shanghai Center for Drug Metabolism and Pharmacokinetics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); Department of Cli
  • Zhang Z; Shanghai Center for Drug Metabolism and Pharmacokinetics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); Department of Cli
  • Lin H; Shanghai Center for Drug Metabolism and Pharmacokinetics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); Department of Cli
  • Zhan Y; Shanghai Center for Drug Metabolism and Pharmacokinetics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); Department of Cli
  • Chen Z; Shanghai Center for Drug Metabolism and Pharmacokinetics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); Department of Cli
  • Zhong D; Shanghai Center for Drug Metabolism and Pharmacokinetics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); Department of Cli
  • Miao L; Shanghai Center for Drug Metabolism and Pharmacokinetics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); Department of Cli
  • Diao X; Shanghai Center for Drug Metabolism and Pharmacokinetics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); University of Chinese Academy of Sciences, Beijing, China (Y.Zhe., M.L., Y.Zha., Z.C., D.Z., X.D.); Department of Cli
Drug Metab Dispos ; 50(6): 798-808, 2022 06.
Article em En | MEDLINE | ID: mdl-34862252
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hiperuricemia / Gota Limite: Humans / Male Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hiperuricemia / Gota Limite: Humans / Male Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article