Chronic unilateral arm lymphedema correlates with increased intima-media thickness in the brachial artery.
Vasa
; 51(1): 19-23, 2022 Jan.
Article
em En
| MEDLINE
| ID: mdl-34872377
ABSTRACT
Drainage of the arterial wall via adventitial lymphatic vessels has been shown to play a pivotal role for vessel wall homeostasis. Also, retrograde cholesterol transport is ensured via this route, but no studies exist to demonstrate that lymphatic stasis would represent a mechanism to initiate atherosclerotic lesion formation in human arteries. To test this hypothesis, we embarked on a simple clinical experiment, assessing wall thickness in limb arteries with lymphedema after surgical intervention, with the contralateral limb serving as control. Using ultrasound imaging, the differential thickness was assessed separately for the three arterial wall layers. The potential of disease progression by lymphostasis was addressed by depiction of longitudinal results according to the time after lymph dissection.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Espessura Intima-Media Carotídea
/
Linfedema
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Vasa
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Alemanha