Natural History of a Mouse Model Overexpressing the Dp71 Dystrophin Isoform.

Lim, Kenji Rowel Q; Shah, Md Nur Ahad; Woo, Stanley; Wilton-Clark, Harry; Zhabyeyev, Pavel; Wang, Faqi; Maruyama, Rika; Oudit, Gavin Y; Yokota, Toshifumi

Lim, Kenji Rowel Q; Shah, Md Nur Ahad; Woo, Stanley; Wilton-Clark, Harry; Zhabyeyev, Pavel; Wang, Faqi; Maruyama, Rika; Oudit, Gavin Y; Yokota, Toshifumi.

Afiliação

Lim KRQ; Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Shah MNA; Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Woo S; Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Wilton-Clark H; Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Zhabyeyev P; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2G3, Canada.
Wang F; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2G3, Canada.
Maruyama R; Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Oudit GY; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2G3, Canada.
Yokota T; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB T6G 2B7, Canada.

Int J Mol Sci ; 22(23)2021 Nov 23.

Article em En | MEDLINE | ID: mdl-34884423

Assuntos

Distrofina/genética; Distrofia Muscular de Duchenne/metabolismo; Isoformas de Proteínas/metabolismo; Animais; Modelos Animais de Doenças; Distrofina/metabolismo; Humanos; Camundongos; Músculo Esquelético/metabolismo; Distrofia Muscular de Duchenne/genética; Miocárdio/metabolismo; Regiões Promotoras Genéticas

Palavras-chave

Dp71; Duchenne muscular dystrophy; WT mice; cardiac dysfunction; del52; dystrophic animal model; dystrophin; hDMDdel52 mice

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Distrofina / Isoformas de Proteínas / Distrofia Muscular de Duchenne Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá

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