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TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.
Xie, Manling; Liu, Yong U; Zhao, Shunyi; Zhang, Lingxin; Bosco, Dale B; Pang, Yuan-Ping; Zhong, Jun; Sheth, Udit; Martens, Yuka A; Zhao, Na; Liu, Chia-Chen; Zhuang, Yongxian; Wang, Liewei; Dickson, Dennis W; Mattson, Mark P; Bu, Guojun; Wu, Long-Jun.
Afiliação
  • Xie M; Department of Neurology, Mayo Clinic, Rochester, MN, USA.
  • Liu YU; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA.
  • Zhao S; Department of Neurology, Mayo Clinic, Rochester, MN, USA. liuy6@foxmail.com.
  • Zhang L; Laboratory for Neuroscience in Health and Disease, Guangzhou First People's Hospital School of Medicine, South China University of Technology, Guangzhou, China. liuy6@foxmail.com.
  • Bosco DB; Department of Neurology, Mayo Clinic, Rochester, MN, USA.
  • Pang YP; Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.
  • Zhong J; Department of Neurology, Mayo Clinic, Rochester, MN, USA.
  • Sheth U; Computer-Aided Molecular Design Laboratory, Mayo Clinic, Rochester, MN, USA.
  • Martens YA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
  • Zhao N; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA.
  • Liu CC; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Zhuang Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Wang L; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Mattson MP; Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.
  • Bu G; Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.
  • Wu LJ; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
Nat Neurosci ; 25(1): 26-38, 2022 01.
Article em En | MEDLINE | ID: mdl-34916658
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Receptores Imunológicos / Microglia / Doenças Neurodegenerativas / Proteínas de Ligação a DNA Limite: Animals Idioma: En Revista: Nat Neurosci Assunto da revista: NEUROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Receptores Imunológicos / Microglia / Doenças Neurodegenerativas / Proteínas de Ligação a DNA Limite: Animals Idioma: En Revista: Nat Neurosci Assunto da revista: NEUROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos